Simoff M J
Division of Pulmonary and Critical Care Medicine, Allergy and Immunology, Henry Ford Hospital, Detroit, Michigan 48202, USA.
Cancer Control. 2001 Jul-Aug;8(4):337-43. doi: 10.1177/107327480100800405.
Patients with lung cancer often have bulky endobronchial disease, endobronchial extension, or airway compression. Many endobronchial treatment modalities are available to supplement traditional therapies for advanced lung cancer.
The author reviews the use of several endobronchial treatment modalities that can augment standard antitumor therapies for advanced lung cancer, including rigid and flexible bronchoscopy, laser therapy, endobronchial prosthesis, and photodynamic therapy.
Since the early 1980s, technical advances in interventional techniques have enhanced symptom-free survival and quality of life for patients with lung cancer. Although interventional procedures are not definitive therapies, they often relieve the strangling sensation produced by airway occlusion.
Endobronchial interventions are important adjuncts in the multimodality management of lung cancer and should become standard considerations in the management of patients with advanced lung cancer. For patients with respiratory symptoms associated with their disease, these interventions provide symptom palliation and improved quality of life.
肺癌患者常伴有较大的支气管内病变、支气管内扩展或气道受压。有多种支气管内治疗方式可用于补充晚期肺癌的传统治疗。
作者回顾了几种可增强晚期肺癌标准抗肿瘤治疗效果的支气管内治疗方式的应用,包括硬质和柔性支气管镜检查、激光治疗、支气管内支架置入术和光动力疗法。
自20世纪80年代初以来,介入技术的技术进步提高了肺癌患者的无瘤生存期和生活质量。虽然介入手术并非确定性治疗,但它们常常能缓解气道阻塞所产生的窒息感。
支气管内介入治疗是肺癌多模式管理中的重要辅助手段,应成为晚期肺癌患者管理中的标准考量。对于伴有呼吸道症状的患者,这些介入治疗可缓解症状并提高生活质量。