Feldman R A
The Royal London Hospital, Whitechapel Road, London E1 1BB, UK.
Aliment Pharmacol Ther. 2001 Jun;15 Suppl 1:2-5. doi: 10.1046/j.1365-2036.2001.00109.x.
This article reviews the data on the epidemiology of gastric cancer, to determine if treatment of an asymptomatic individual can be justified. It reviews retrospective and prospective case-control studies of gastric cancer in Italy and other countries. Mucosa-associated lymphoid tissue lymphoma is associated with Helicobacter pylori infection. The risk of noncardia gastric cancer is higher (4-fold or greater) in those with H. pylori infection. Although no studies have shown prevention following treatment, eradication of asymptomatic H. pylori infection in an individual in the age group 40 or lower may be expected to reduce the risk of gastric cancer.
本文回顾了有关胃癌流行病学的数据，以确定对无症状个体进行治疗是否合理。它回顾了意大利和其他国家关于胃癌的回顾性和前瞻性病例对照研究。黏膜相关淋巴组织淋巴瘤与幽门螺杆菌感染有关。幽门螺杆菌感染者患非贲门胃癌的风险更高（4倍或更高）。虽然尚无研究表明治疗后可预防，但预计根除40岁及以下个体的无症状幽门螺杆菌感染可降低患胃癌的风险。
