诱导型一氧化氮合酶与沙门氏菌感染。
Inducible nitric oxide synthase and Salmonella infection.
作者信息
Cherayil B J, Antos D
机构信息
Mucosal Immunology Laboratory, Combined Program in Pediatric Gastroenterology and Nutrition, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA.
出版信息
Microbes Infect. 2001 Jul;3(9):771-6. doi: 10.1016/s1286-4579(01)01428-9.
Abstract
Salmonella infection is associated with the increased expression of inducible nitric oxide synthase in macrophages and other cells. This review summarizes current knowledge of the molecular mechanisms involved in the induction process, and discusses the functional significance of nitric oxide production in the context of host defense against Salmonella.
摘要
沙门氏菌感染与巨噬细胞及其他细胞中诱导型一氧化氮合酶的表达增加有关。本综述总结了诱导过程中涉及的分子机制的当前知识，并在宿主抵御沙门氏菌的背景下讨论了一氧化氮产生的功能意义。
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