McGrew R N, Wilson R S, Havener W H
Otolaryngology. 1978 Jan-Feb;86(1):ORL-152-7.
The sudden occurrence of unilateral and bilateral blindness, as reported in the literature from the personal experiences of numerous qualified investigators, occurring in humans and producing such catastrophic effects seems to mandate experimental effort to try and answer three basic questions: (1) Can an animal model be found which will demonstrate similar retinopathy for study? (2) If such a model is found, what mechanisms are involved in the production of the retinal pathologic changes? (3) What are the characteristics of the drug or drug combinations necessary to produce these pathologic changes?
正如众多资深研究者在文献中根据个人经验所报告的那样，人类突然出现的单侧和双侧失明会产生如此灾难性的影响，这似乎要求进行实验研究，以尝试回答三个基本问题：（1）能否找到一种动物模型来展示类似的视网膜病变以供研究？（2）如果找到这样的模型，视网膜病理变化的产生涉及哪些机制？（3）产生这些病理变化所需的药物或药物组合有哪些特征？
