Berger M J, Taymor M L, Patton W C
Fertil Steril. 1975 Jul;26(7):619-26.
Gonadotropin levels and secretory patterns were studied in 28 oligomenorrheic patients with various types of polycystic ovary disease (PCO). On the basis of ovarian morphology and histology, the patients PCOuld be separated into two distinct categories arbitarily designated "typical" (type I) and "atypical" (type II) PCO. Although no differences were noted in symptomatology or 17-ketosteroid, testosterone, or follicle-stimulating hormone levels, the 12 type I patients demonstrated widely fluctuating, but markedly elevated, luteinizing hormone (LH) levels, while the 16 type II patients demonstrated lower and less fluctuating LH levels which were comparable to those found during the normal follicular phase. It is likely that type I PCO is a distinct entity similar to that described by Stein and Leventhal, while type II co represents a heterogenous spectrum of disorders, many of which remain obscure.
对28例患有各种类型多囊卵巢疾病(PCO)的月经过少患者的促性腺激素水平和分泌模式进行了研究。根据卵巢形态学和组织学,这些PCO患者可被任意分为两个不同类别,分别称为“典型”(I型)和“非典型”(II型)PCO。虽然在症状学或17-酮类固醇、睾酮或促卵泡激素水平方面未发现差异,但12例I型患者的促黄体生成素(LH)水平波动很大,但明显升高,而16例II型患者的LH水平较低且波动较小,与正常卵泡期的水平相当。I型PCO可能是一种与斯坦因和莱文塔尔所描述的类似的独特病症,而II型PCO则代表了一系列异质性疾病,其中许多疾病仍不清楚。