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典型和非典型多囊卵巢疾病患者的促性腺激素水平及分泌模式

Gonadotropin levels and secretory patterns in patients with typical and atypical polycystic ovarian disease.

作者信息

Berger M J, Taymor M L, Patton W C

出版信息

Fertil Steril. 1975 Jul;26(7):619-26.

PMID:1149897
Abstract

Gonadotropin levels and secretory patterns were studied in 28 oligomenorrheic patients with various types of polycystic ovary disease (PCO). On the basis of ovarian morphology and histology, the patients PCOuld be separated into two distinct categories arbitarily designated "typical" (type I) and "atypical" (type II) PCO. Although no differences were noted in symptomatology or 17-ketosteroid, testosterone, or follicle-stimulating hormone levels, the 12 type I patients demonstrated widely fluctuating, but markedly elevated, luteinizing hormone (LH) levels, while the 16 type II patients demonstrated lower and less fluctuating LH levels which were comparable to those found during the normal follicular phase. It is likely that type I PCO is a distinct entity similar to that described by Stein and Leventhal, while type II co represents a heterogenous spectrum of disorders, many of which remain obscure.

摘要

对28例患有各种类型多囊卵巢疾病(PCO)的月经过少患者的促性腺激素水平和分泌模式进行了研究。根据卵巢形态学和组织学,这些PCO患者可被任意分为两个不同类别,分别称为“典型”(I型)和“非典型”(II型)PCO。虽然在症状学或17-酮类固醇、睾酮或促卵泡激素水平方面未发现差异,但12例I型患者的促黄体生成素(LH)水平波动很大,但明显升高,而16例II型患者的LH水平较低且波动较小,与正常卵泡期的水平相当。I型PCO可能是一种与斯坦因和莱文塔尔所描述的类似的独特病症,而II型PCO则代表了一系列异质性疾病,其中许多疾病仍不清楚。

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引用本文的文献

1
The polycystic ovary syndrome: the first 150 years of study.多囊卵巢综合征:研究的前150年
F S Rep. 2022 Dec 22;4(1):2-18. doi: 10.1016/j.xfre.2022.12.002. eCollection 2023 Mar.
2
Ultrasound study of ovarian morphology in women with polycystic ovary syndrome before and during treatment with an oestrogen/progestogen preparation.多囊卵巢综合征女性在接受雌激素/孕激素制剂治疗前及治疗期间的卵巢形态超声研究。
Arch Gynecol. 1983;234(2):87-93. doi: 10.1007/BF00207680.
3
Polycystic ovary syndrome: an enigma awaiting solution.多囊卵巢综合征:一个亟待解决的谜团。
Bull N Y Acad Med. 1987 Mar;63(2):134-55.
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Polycystic ovarian disease: endocrinological parameters with specific reference to growth hormone and somatomedin-C.多囊卵巢疾病:特别涉及生长激素和胰岛素样生长因子 -C的内分泌学参数
Arch Gynecol Obstet. 1988;243(1):13-36. doi: 10.1007/BF00931548.
5
Effects of obesity on gonadotropin secretion in patients with polycystic ovarian disease.
J Endocrinol Invest. 1986 Apr;9(2):139-44. doi: 10.1007/BF03348085.
6
Characterization of the inappropriate gonadotropin secretion in polycystic ovary syndrome.多囊卵巢综合征中不适当促性腺激素分泌的特征
J Clin Invest. 1976 May;57(5):1320-9. doi: 10.1172/JCI108400.