Härnryd C, Bjerkenstedt L, Grimm V E, Sedvall G
Psychopharmacology (Berl). 1979 Aug 8;64(2):131-4. doi: 10.1007/BF00496052.
The effect of ECT on concentrations of monoamine metabolites in lumbar CSF of psychotic women with a schizophrenic symptomatology was examined. After a series of ECT there was a significant reduction of the concentration of the major noradrenaline metabolite, MOPEG. Levels of HVA, 5-HIAA, prolactin, or total protein in CSF were not significantly influenced by treatment. The results indicate a specific alteration of central noradrenaline metabolism in relation to ECT.
研究了电休克治疗（ECT）对有精神分裂症症状的精神病女性腰椎脑脊液中一元胺代谢物浓度的影响。经过一系列ECT治疗后，主要去甲肾上腺素代谢物3-甲氧基-4-羟基苯乙二醇（MOPEG）的浓度显著降低。脑脊液中高香草酸（HVA）、5-羟吲哚乙酸（5-HIAA）、催乳素或总蛋白水平未受治疗的显著影响。结果表明，与ECT相关的中枢去甲肾上腺素代谢有特定改变。
