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[氧化应激、疾病与抗氧化治疗]

[Oxidative stress, diseases and antioxidant treatment].

作者信息

Elejalde Guerra J I

机构信息

Servicio de Medicina Interna del Hospital de Navarra.

出版信息

An Med Interna. 2001 Jun;18(6):326-35.

PMID:11503582
Abstract

Oxidation is a biochemical process of loss of electrons associated with another of reception called reduction. This process is capital for life, because it takes part in the production of cellular energy. Oxidative stress appears when oxidation is excessive. This reality is complex in all biological levels, and cannot be measured or defined by a single parameter. A great number of diseases have been related to oxidative stress and generation of free radicals. For this reason, antioxidant therapies and diets (such as mediterranean diet) rich or enriched with antioxidants seem to prevent or at least to attenuate the organic deterioration originated by an excessive oxidative stress.

摘要

氧化是一个与另一个称为还原的电子接收过程相关的电子丢失的生化过程。这个过程对生命至关重要,因为它参与细胞能量的产生。当氧化过度时就会出现氧化应激。这一现象在所有生物层面都很复杂,无法通过单一参数进行测量或定义。大量疾病都与氧化应激和自由基的产生有关。因此,抗氧化疗法以及富含或添加了抗氧化剂的饮食(如地中海饮食)似乎可以预防或至少减轻由过度氧化应激引起的机体退化。

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