Wulffraat N, van der Net J J, Ruperto N, Kamphuis S, Prakken B J, Ten Cate R, Van Soesbergen R M, Van Rossum M A, Raat H, Landgraf J M, Kuis W
UMC Utrecht-Wilhelmina Kinderziekenhuis, Utrecht, Netherlands.
Clin Exp Rheumatol. 2001 Jul-Aug;19(4 Suppl 23):S111-5.
We report herein the results of the cross-cultural adaptation and validation into the Dutch language of the parent's version of two health related quality of life instruments. The Childhood Health Assessment Questionnaire (CHAQ) is a disease specific health instrument that measures functional ability in daily living activities in children with juvenile idiopathic arthritis (JIA). The Child Health Questionnaire (CHQ) is a generic health instrument designed to capture the physical and psychosocial well-being of children independently from the underlying disease. The Dutch CHAQ was fully validated with 3 forward and 3 backward translations while the CHQ was already published and therefore it was revalidated. A total of 180 subjects were enrolled: 100 patients with JIA (17% systemic onset, 31% polyarticular onset, 18% extended oligoarticular subtype, and 34% persistent oligoarticular subtype) and 80 healthy children. The CHAQ clinically discriminated between healthy subjects and JIA patients, with the systemic, polyarticular and extended oligoarticular subtypes having a higher degree of disability, pain, and a lower overall well-being when compared to their healthy peers. Also the CHQ clinically discriminated between healthy subjects and JIA patients, with the systemic onset, polyarticular onset and extended oligoarticular subtypes having a lower physical and psychosocial well-being when compared to their healthy peers. In conclusion the Dutch version of the CHAQ-CHQ is a reliable, and valid tool for the functional, physical and psychosocial assessment of children with JIA.
我们在此报告两种与健康相关的生活质量工具家长版跨文化改编并验证为荷兰语的结果。儿童健康评估问卷（CHAQ）是一种针对疾病的健康工具，用于测量幼年特发性关节炎（JIA）患儿日常生活活动中的功能能力。儿童健康问卷（CHQ）是一种通用健康工具，旨在独立于潜在疾病来评估儿童的身体和心理社会福祉。荷兰语版CHAQ通过3次正向翻译和3次反向翻译进行了全面验证，而CHQ已经发表，因此进行了重新验证。总共招募了180名受试者：100名JIA患者（17%全身型发病，31%多关节型发病，18%扩展性少关节型亚型，34%持续性少关节型亚型）和80名健康儿童。CHAQ在临床上能够区分健康受试者和JIA患者，全身型、多关节型和扩展性少关节型亚型与健康同龄人相比，残疾程度更高、疼痛更严重，总体幸福感更低。CHQ在临床上也能区分健康受试者和JIA患者，全身型发病、多关节型发病和扩展性少关节型亚型与健康同龄人相比，身体和心理社会福祉更低。总之，荷兰语版的CHAQ-CHQ是评估JIA患儿功能、身体和心理社会状况的可靠且有效的工具。
