Ruperto N, Ravelli A, Pistorio A, Malattia C, Viola S, Cavuto S, Alessio M, Alpigiani M G, Buoncompagni A, Corona F, Cortis E, Falcini F, Gerloni V, Lepore L, Sardella M L, Strano C G, Zulian F, Gado-West L, Tortorelli A, Fantini F, Martini A
Laboratorio di Informatica Medica, IRCCS S. Matteo, Università di Pavia, Italy.
Clin Exp Rheumatol. 2001 Jul-Aug;19(4 Suppl 23):S91-5.
We report herein the results of the cross-cultural adaptation and validation into the Italian language of the parent's version of two health related quality of life instruments. The Childhood Health Assessment Questionnaire (CHAQ) is a disease specific health instrument that measures functional ability in daily living activities in children with juvenile idiopathic arthritis (JIA). The Child Health Questionnaire (CHQ) is a generic health instrument designed to capture the physical and psychosocial well-being of children independently from the underlying disease. The Italian CHAQ was already published in the literature and was therefore revalidated while the Italian CHQ was fully cross culturally adapted with 3 forward and 3 backward translations, and than validated. A total of 1,192 subjects were enrolled: 404 patients with JIA (16% systemic onset, 31% polyarticular onset, 21% extended oligoarticular subtype, and 32% persistent oligoarticular subtype) and 788 healthy children. The CHAQ clinically discriminated between healthy subjects and JIA patients, with the systemic, polyarticular and extended oligoarticular subtypes having a higher degree of disability, pain, and a lower overall well-being when compared to their healthy peers. Also the CHQ clinically discriminated between healthy subjects and JIA patients, with the systemic onset, polyarticular onset and extended oligoarticular subtypes having a lower physical and psychosocial well-being when compared to their healthy peers. In conclusion the Italian version of the CHAQ-CHQ are reliable, and valid tools for the functional, physical and psychosocial assessment of children with JIA.
我们在此报告两种与健康相关的生活质量工具家长版的跨文化调适及意大利语验证结果。儿童健康评估问卷（CHAQ）是一种针对疾病的健康工具，用于测量幼年特发性关节炎（JIA）患儿的日常生活活动功能能力。儿童健康问卷（CHQ）是一种通用健康工具，旨在独立于潜在疾病来获取儿童的身体和心理社会健康状况。意大利语版的CHAQ已在文献中发表，因此进行了重新验证，而意大利语版的CHQ则通过3次正向翻译和3次反向翻译进行了全面的跨文化调适，然后进行了验证。总共招募了1192名受试者：404例JIA患者（16%为全身型起病，31%为多关节型起病，21%为扩展性少关节型亚型，32%为持续性少关节型亚型）和788名健康儿童。CHAQ在临床上能够区分健康受试者和JIA患者，全身型、多关节型和扩展性少关节型亚型与健康同龄人相比，残疾程度更高、疼痛更严重，总体幸福感更低。CHQ在临床上也能够区分健康受试者和JIA患者，全身型起病、多关节型起病和扩展性少关节型亚型与健康同龄人相比，身体和心理社会幸福感更低。总之，意大利语版的CHAQ-CHQ是评估JIA患儿功能、身体和心理社会状况的可靠且有效的工具。
