Hardt J, Buchwald D, Wilks D, Sharpe M, Nix W A, Egle U T
Department of Psychosomatic Medicine and Psychotherapy, University of Mainz, Untere Zahlbacher 8, D-55101, Mainz, Germany.
J Psychosom Res. 2001 Aug;51(2):431-4. doi: 10.1016/s0022-3999(01)00220-3.
Chronic fatigue syndrome (CFS) has been reported worldwide. Our objectives were to determine if patients from different countries have similar profiles of impairments.
Health-related quality of life (HRQoL) was assessed in 740 CFS patients in the US, 82 in the UK, and 65 in Germany using the eight subscales of the Short-Form General Health Survey (SF-36). To examine the internal structure, factor analyses were performed.
Overall, there was a remarkable similarity in HRQoL among all CFS patients, regardless of location. Patients scored two to three standard deviations below normal on six subscales and one standard deviation below normal on the other two subscales. Factor analysis suggested a two-factor model where the same six subscales constitute the first factor and the two others the second factor.
HRQoL is poor in CFS patients from three countries. This study is a first step towards conducting further comparative cross-cultural and international studies.
慢性疲劳综合征（CFS）在全球范围内均有报道。我们的目的是确定来自不同国家的患者是否具有相似的损伤特征。
使用简短通用健康调查问卷（SF - 36）的八个分量表，对美国的740名CFS患者、英国的82名患者和德国的65名患者的健康相关生活质量（HRQoL）进行了评估。为了检验内部结构，进行了因子分析。
总体而言，所有CFS患者的HRQoL存在显著相似性，无论其所在位置如何。患者在六个分量表上的得分比正常水平低两到三个标准差，在另外两个分量表上比正常水平低一个标准差。因子分析表明存在一个双因子模型，其中相同的六个分量表构成第一个因子，另外两个构成第二个因子。
来自三个国家的CFS患者的HRQoL较差。本研究是开展进一步比较性跨文化和国际研究的第一步。
