Ottó S, Verzár R, Somogyi E
Z Rechtsmed. 1979 Jul 17;83(2):101-4. doi: 10.1007/BF02092265.
Electric precipitation is a method in serological diagnostics (determination of species-specificity). Since serum protein fractions (especially immunoglobulins) and extracts from blood stains migrate in agar-gel at pH 8.2--8.6 towards the cathode they cannot be used for the determination of the species specificity. By a chemical method using glutaraldehyde authors have produced an albumin-immunoglobulin complex, altering in this way the direction of electrophoretic mobility. Treatment of the blood samples with glutaraldehyde increases the sensitivity and realiability of the method.
电沉淀法是血清学诊断(物种特异性测定)中的一种方法。由于血清蛋白组分(尤其是免疫球蛋白)和血渍提取物在pH 8.2 - 8.6的琼脂凝胶中向阴极迁移,因此它们不能用于物种特异性的测定。作者通过使用戊二醛的化学方法制备了白蛋白 - 免疫球蛋白复合物,从而改变了电泳迁移的方向。用戊二醛处理血样可提高该方法的灵敏度和可靠性。