Kristiansen B E, Sørensen B, Spanne O, Bjorvatn B
Scand J Infect Dis. 1985;17(1):19-24. doi: 10.3109/00365548509070415.
In September 1981 a soldier died from meningococcal septicemia in a military camp in Mid-Norway. Soon afterwards one of his room-mates was transferred to a military camp in Northern-Norway where he shared sleeping quarters (room 7D) with 5 other soldiers of whom 2 fell ill with meningococcal disease 1 month later. Throat cultures were obtained from all 128 soldiers at the military camp in Northern-Norway; 41 (32%) harboured meningococci in their throats. The 3 invasive isolates and the isolates from the 4 healthy carriers at room 7D were all group B and type 15 meningococci. However, by DNA fingerprinting we could identify at least 2, probably 3, different individual strains among these 7 isolates. None of these strains were isolated from soldiers outside room 7D. By use of a B15 whole-bacterium ELISA method we showed that the levels of antimeningococcal IgG antibodies in the sera of the two cases at room 7D were low (18 and 28 OD units) compared with the mean IgG levels in the sera of their 4 healthy room mates (1150 OD units) and the mean IgG in the sera from all healthy soldiers (472 OD units).
1981年9月，挪威中部一个军营里有一名士兵死于脑膜炎球菌败血症。不久之后，他的一名室友被转移到挪威北部的一个军营，在那里他与另外5名士兵共用宿舍（7D房间），其中2人在1个月后患上了脑膜炎球菌病。对挪威北部军营里的所有128名士兵进行了咽喉培养；41人（32%）咽喉中带有脑膜炎球菌。3株侵袭性分离株以及7D房间4名健康携带者的分离株均为B群15型脑膜炎球菌。然而，通过DNA指纹图谱分析，我们在这7株分离株中至少鉴定出了2种，可能是3种不同的个体菌株。这些菌株均未从7D房间以外的士兵中分离出来。通过使用B15全菌ELISA方法，我们发现7D房间两名病例血清中的抗脑膜炎球菌IgG抗体水平较低（分别为18和28 OD单位），相比之下，他们4名健康室友血清中的平均IgG水平为（1150 OD单位），所有健康士兵血清中的平均IgG水平为（472 OD单位）。
