核酸内切酶活性与属于人类腺病毒三个亚组的血清型的关联。
Association of endonuclease activity with serotypes belonging to the three subgroups of human adenoviruses.
作者信息
Marusyk R G, Morgan A R, Wadell G
出版信息
J Virol. 1975 Aug;16(2):456-8. doi: 10.1128/JVI.16.2.456-458.1975.
Abstract
Endonuclease activity has been detected in association with highly purified virions, pentons, and/or dodecons of adenovirus types 2, 3, 5, 9, 12, 15, and 16. Only single-strand scissions in substrate DNA were detected. The nuclease activity was detected by a highly sensitive ethidium bromide fluorimetric assay procedure.
摘要
在与2型、3型、5型、9型、12型、15型和16型腺病毒的高度纯化病毒粒子、五邻体和/或十二聚体相关联的情况下，已检测到核酸内切酶活性。在底物DNA中仅检测到单链切割。核酸酶活性通过一种高度灵敏的溴化乙锭荧光测定法检测。
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