• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

两种犬腺病毒的生物物理比较

Biophysical comparison of two canine adenoviruses.

作者信息

Marusyk R G, Norrby E, Lundqvist U

出版信息

J Virol. 1970 Apr;5(4):507-12. doi: 10.1128/JVI.5.4.507-512.1970.

DOI:10.1128/JVI.5.4.507-512.1970
PMID:4318090
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC376033/
Abstract

The two canine adenoviruses, infectious canine hepatitis (ICH) virus and infectious canine laryngotracheitis (ICL) virus (also designated as Toronto A26/61 virus), were studied with respect to their morphology and the biological properties of their soluble components. The two viruses were found to be composed of soluble components similar to, and carrying biological activities corresponding to, those of the human adenoviruses after fractionation by rate zonal centrifugation and anion-exchange chromatography. The following soluble components were identified: hexons (carrying a common group-specific complement-fixing antigen), penton oligomers (complete soluble hemagglutinin), and penton and fiber monomers (incomplete soluble hemagglutinins). The latter were indicated by hemagglutination enhancement with selected antisera directed against human adenovirus soluble components. Elution characteristics of corresponding components of the two viruses in anion-exchange chromatography experiments were distinctly different. Electron microscopic examination of purified virions and soluble components revealed the fiber component of ICL virus to be 35 to 37 nm in length, and that of ICH virus to be 25 to 27 nm long.

摘要

对两种犬腺病毒，即犬传染性肝炎（ICH）病毒和犬传染性喉气管炎（ICL）病毒（也称为多伦多A26/61病毒），就其形态以及可溶性成分的生物学特性进行了研究。通过速率区带离心和阴离子交换色谱法分级分离后发现，这两种病毒的可溶性成分与人类腺病毒的相似，并具有与之对应的生物学活性。鉴定出了以下可溶性成分：六邻体（携带共同的群特异性补体结合抗原）、五邻体寡聚体（完整的可溶性血凝素）以及五邻体和纤维单体（不完整的可溶性血凝素）。针对人类腺病毒可溶性成分的特定抗血清通过血凝增强作用表明了后者的存在。在阴离子交换色谱实验中，两种病毒相应成分的洗脱特性明显不同。对纯化病毒粒子和可溶性成分的电子显微镜检查显示，ICL病毒的纤维成分长度为35至37纳米，ICH病毒的纤维成分长度为25至27纳米。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/deea/376033/2d7c852fd666/jvirol00292-0099-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/deea/376033/bcaecb17fcf4/jvirol00292-0098-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/deea/376033/2d7c852fd666/jvirol00292-0099-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/deea/376033/bcaecb17fcf4/jvirol00292-0098-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/deea/376033/2d7c852fd666/jvirol00292-0099-a.jpg

相似文献

1
Biophysical comparison of two canine adenoviruses.两种犬腺病毒的生物物理比较
J Virol. 1970 Apr;5(4):507-12. doi: 10.1128/JVI.5.4.507-512.1970.
2
Comparative studies on the soluble components of adenovirus types 9 and 15 and the intermediate strain 9-15.9型和15型腺病毒以及中间株9-15可溶性成分的比较研究。
J Virol. 1968 Oct;2(10):1200-10. doi: 10.1128/JVI.2.10.1200-1210.1968.
3
Immunological basis of the adenovirus 8-9 cross-reaction.腺病毒8型与9型交叉反应的免疫学基础
J Virol. 1970 Dec;6(6):782-7. doi: 10.1128/JVI.6.6.782-787.1970.
4
The proteins of adenovirus type 5.5型腺病毒的蛋白质
Arch Gesamte Virusforsch. 1970;29(1):1-24. doi: 10.1007/BF01253875.
5
The soluble hemagglutinins of adenoviruses belonging to Rosen's subgroup 3. I. The rapidly sedimenting hemagglutinin.属于罗森3型亚组的腺病毒可溶性血凝素。I. 快速沉降的血凝素。
Arch Gesamte Virusforsch. 1969;26(1):33-52. doi: 10.1007/BF01241174.
6
Separation and characterization of soluble adenovirus type 9 components.9型可溶性腺病毒成分的分离与鉴定
J Virol. 1967 Dec;1(6):1101-8. doi: 10.1128/JVI.1.6.1101-1108.1967.
7
Separation of infectious canine hepatitis virus antigens: soluble antigens.犬传染性肝炎病毒抗原的分离：可溶性抗原
Acta Virol. 1971 Mar;15(2):167-70.
8
Mosaics of capsid components produced by cocultivation of certain human adenoviruses in vitro.通过某些人类腺病毒体外共培养产生的衣壳成分镶嵌体。
Virology. 1971 May;44(2):383-95. doi: 10.1016/0042-6822(71)90269-8.
9
Soluble components of adenovirus type 8.8型腺病毒的可溶性成分
J Virol. 1970 Oct;6(4):406-13. doi: 10.1128/JVI.6.4.406-413.1970.
10
Identification of soluble components of adenovirus type 11.11型腺病毒可溶性成分的鉴定
J Gen Virol. 1968 Jan;2(1):123-33. doi: 10.1099/0022-1317-2-1-123.

引用本文的文献

1
Canine Adenoviruses in Wildlife: Role in At-Risk Species Conservation and Interface with Domestic Animals.野生动物中的犬腺病毒：在濒危物种保护中的作用以及与家畜的关联
Pathogens. 2025 Feb 18;14(2):200. doi: 10.3390/pathogens14020200.
2
Difference Analysis Between Canine Adenovirus Types 1 And 2.犬腺病毒 1 型和 2 型的差异分析。
Front Cell Infect Microbiol. 2022 Mar 11;12:854876. doi: 10.3389/fcimb.2022.854876. eCollection 2022.
3
Canine adenoviruses and herpesvirus.犬腺病毒和疱疹病毒。

本文引用的文献

1
Association of Canine Adenovirus (Toronto A 26/61) with an Outbreak of Laryngotracheitis ("Kennel Cough"): A Preliminary Report.犬腺病毒（多伦多A 26/61株）与喉气管炎（“犬窝咳”）暴发的关联：初步报告
Can Vet J. 1962 Aug;3(8):238-47.
2
Complement fixation with Brunhilde and Lansing poliomyelitis viruses propagated in tissue culture.用在组织培养中繁殖的布伦希尔德株和兰辛株脊髓灰质炎病毒进行补体结合试验。
Proc Soc Exp Biol Med. 1952 Feb;79(2):296-300. doi: 10.3181/00379727-79-19357.
3
Antigenic structure of non-infectious adenovirus materials.非感染性腺病毒材料的抗原结构
Vet Clin North Am Small Anim Pract. 2008 Jul;38(4):799-814, viii. doi: 10.1016/j.cvsm.2008.02.006.
4
Forty years of canine vaccination.四十年的犬类疫苗接种
Adv Vet Med. 1999;41:309-24. doi: 10.1016/s0065-3519(99)80023-8.
5
Immunological and molecular comparison of fowl adenovirus serotypes 4 and 10.禽腺病毒血清型4和10的免疫学及分子比较
Arch Virol. 1995;140(3):491-501. doi: 10.1007/BF01718426.
6
Interspecific differences between the DNA restriction profiles of canine adenoviruses.犬腺病毒DNA限制性酶切图谱的种间差异
Experientia. 1984 May 15;40(5):482. doi: 10.1007/BF01952396.
7
Macromolecular content of inclusions produced by a canine adenovirus.犬腺病毒产生的包涵体的大分子含量
J Virol. 1972 Oct;10(4):801-9. doi: 10.1128/JVI.10.4.801-809.1972.
8
Soluble antigen of blue-tongue virus.蓝舌病毒可溶性抗原
Infect Immun. 1972 Apr;5(4):467-73. doi: 10.1128/iai.5.4.467-473.1972.
9
Association of endonuclease activity with serotypes belonging to the three subgroups of human adenoviruses.核酸内切酶活性与属于人类腺病毒三个亚组的血清型的关联。
J Virol. 1975 Aug;16(2):456-8. doi: 10.1128/JVI.16.2.456-458.1975.
Nature. 1960 May 14;186:571-2. doi: 10.1038/186571a0.
4
The effect of ion concentration and pH on the thermal stability of a canine adenovirus.离子浓度和pH值对犬腺病毒热稳定性的影响
Can J Microbiol. 1967 Sep;13(9):1139-49. doi: 10.1139/m67-158.
5
Some physical and growth characteristics of a canine adenovirus isolated from dogs with laryngotracheitis.从患有喉气管炎的犬只中分离出的一种犬腺病毒的一些物理和生长特性。
Can J Microbiol. 1966 Apr;12(2):303-11. doi: 10.1139/m66-041.
6
A study of the pathogenicity of a canine adenovirus (Toronto A26-61) for dogs.
Am J Vet Res. 1969 Jul;30(7):1187-93.
7
The soluble hemagglutinins of adenoviruses belonging to Rosen's subgroup 3. II. The slowly sedimenting hemagglutinin.属于罗森3型亚组的腺病毒的可溶性血凝素。II. 沉降缓慢的血凝素。
Arch Gesamte Virusforsch. 1969;26(1):53-62. doi: 10.1007/BF01241175.
8
The soluble hemagglutinins of adenoviruses belonging to Rosen's subgroup 3. I. The rapidly sedimenting hemagglutinin.属于罗森3型亚组的腺病毒可溶性血凝素。I. 快速沉降的血凝素。
Arch Gesamte Virusforsch. 1969;26(1):33-52. doi: 10.1007/BF01241174.
9
Separation and characterization of soluble adenovirus type 9 components.9型可溶性腺病毒成分的分离与鉴定
J Virol. 1967 Dec;1(6):1101-8. doi: 10.1128/JVI.1.6.1101-1108.1967.
10
Fiber-associated incomplete and complete hemagglutinins of adenovirus type 6.6型腺病毒的纤维相关不完全和完全血凝素
Arch Gesamte Virusforsch. 1969;28(2):239-44. doi: 10.1007/BF01249389.