合成四肽埃皮塔隆可恢复衰老猴子中紊乱的神经内分泌调节。
Synthetic tetrapeptide epitalon restores disturbed neuroendocrine regulation in senescent monkeys.
作者信息
Khavinson V, Goncharova N, Lapin B
机构信息
St. Petersburg Institute of Bioregulation and Gerontology, 3 Dynamo Prospect, 197110 St. Petersburg, Russia.
出版信息
Neuro Endocrinol Lett. 2001 Aug;22(4):251-4.
UNLABELLED
The OBJECTIVE of this research was to investigate the regulatory effect of Epitalon on the production of melatonin and cortisol in senescent monkeys.
MATERIAL AND METHODS
We investigated the character of melatonin and cortisol secretion by immunoferment assay in Epitalon-administered female Macaca mulatta in different age periods.
RESULTS
Epitalon was proven to significantly stimulate melatonin synthesis in senescent monkeys in the evening, thereby normalising the circadian rhythm of cortisol secretion.
未标注
本研究的目的是调查埃替隆对衰老猴子褪黑素和皮质醇分泌的调节作用。
材料与方法
我们通过免疫酶测定法研究了不同年龄段接受埃替隆治疗的雌性恒河猴中褪黑素和皮质醇的分泌特征。
结果
已证实埃替隆能显著刺激衰老猴子在夜间合成褪黑素，从而使皮质醇分泌的昼夜节律正常化。
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