Linde K, Hondras M, Vickers A, ter Riet G, Melchart D
Centre for Complementary Medicine Research, Department of Internal Medicine II, Technische Universität, München, Kaiserstr 9, 80801 München, Germany.
BMC Complement Altern Med. 2001;1:4. doi: 10.1186/1472-6882-1-4. Epub 2001 Jul 20.
Complementary therapies are widespread but controversial. We aim to provide a comprehensive collection and a summary of systematic reviews of clinical trials in three major complementary therapies (acupuncture, herbal medicine, homeopathy). This article is dealing with homeopathy. Potentially relevant reviews were searched through the register of the Cochrane Complementary Medicine Field, the Cochrane Library, Medline, and bibliographies of articles and books. To be included articles had to review prospective clinical trials of homeopathy; had to describe review methods explicitly; had to be published; and had to focus on treatment effects. Information on conditions, interventions, methods, results and conclusions was extracted using a pretested form and summarized descriptively.
Eighteen out of 22 potentially relevant reviews preselected in the screening process met the inclusion criteria. Six reviews addressed the question whether homeopathy is effective across conditions and interventions. The majority of available trials seem to report positive results but the evidence is not convincing. For isopathic nosodes for allergic conditions, oscillococcinum for influenza-like syndromes and galphimia for pollinosis the evidence is promising while in other areas reviewed the results are equivocal.
Reviews on homeopathy often address general questions. While the evidence is promising for some topics the findings of the available reviews are unlikely to end the controversy on this therapy.
补充疗法广泛应用但存在争议。我们旨在全面收集并总结针对三种主要补充疗法(针灸、草药、顺势疗法)的临床试验系统评价。本文讨论顺势疗法。通过Cochrane补充医学领域注册库、Cochrane图书馆、Medline以及文章和书籍的参考文献搜索潜在相关的综述。纳入的文章必须是对顺势疗法前瞻性临床试验的综述;必须明确描述综述方法;必须已发表;且必须关注治疗效果。使用预先测试的表格提取有关疾病、干预措施、方法、结果和结论的信息,并进行描述性总结。
在筛选过程中预先选定的22篇潜在相关综述中,有18篇符合纳入标准。6篇综述探讨了顺势疗法在各种疾病和干预措施中是否有效的问题。大多数现有试验似乎报告了阳性结果,但证据并不令人信服。对于过敏性疾病的同种病源菌苗、流感样综合征的 Oscillococcinum以及花粉症的 Galphimia,证据很有前景,而在其他综述领域结果则不明确。
关于顺势疗法的综述常常涉及一般性问题。虽然某些主题的证据很有前景,但现有综述的结果不太可能终结对这种疗法的争议。