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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Monatsschr Kinderheilkd (1902). 1975 Jul;123(7):545-7.

With a constant plasma concentration of Ampicillin the ratio of concentration in the cerebrospinal fluid to concentration in the plasma reaches a constant value after 2 hrs in patients with and without serous meningitis. 2. Patients without serous meningitis have a value of 0.025, patients with serous meningitis a value of 0.061. 3. From this it can be calculated that Ampicillin passes two and a half times faster through inflamed meningeal membranes than unaffected membranes.

对于血浆中氨苄西林浓度恒定的情况，在患有和未患有浆液性脑膜炎的患者中，脑脊液浓度与血浆浓度之比在2小时后达到恒定值。2. 未患浆液性脑膜炎的患者该比值为0.025，患有浆液性脑膜炎的患者该比值为0.061。3. 由此可以计算出，氨苄西林通过发炎脑膜的速度比未受影响的脑膜快两倍半。

Monatsschr Kinderheilkd (1902). 1975 Jul;123(7):545-7.

With a constant plasma concentration of Ampicillin the ratio of concentration in the cerebrospinal fluid to concentration in the plasma reaches a constant value after 2 hrs in patients with and without serous meningitis. 2. Patients without serous meningitis have a value of 0.025, patients with serous meningitis a value of 0.061. 3. From this it can be calculated that Ampicillin passes two and a half times faster through inflamed meningeal membranes than unaffected membranes.

对于血浆中氨苄西林浓度恒定的情况，在患有和未患有浆液性脑膜炎的患者中，脑脊液浓度与血浆浓度之比在2小时后达到恒定值。2. 未患浆液性脑膜炎的患者该比值为0.025，患有浆液性脑膜炎的患者该比值为0.061。3. 由此可以计算出，氨苄西林通过发炎脑膜的速度比未受影响的脑膜快两倍半。