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用于确定睡眠性阻塞性睡眠呼吸暂停患者上气道狭窄部位的柔性管反射测量法。

Flextube reflectometry for determination of sites of upper airway narrowing in sleeping obstructive sleep apnoea patients.

作者信息

Faber C E, Hilberg O, Jensen F T, Norregaard O, Grymer L

机构信息

Department of Otorhinolaryngology, University Hospital, Aarhus, Denmark.

出版信息

Respir Med. 2001 Aug;95(8):639-48. doi: 10.1053/rmed.2001.1125.

Abstract

The aim of this study was to examine a new technique based on sound reflections in a flexible tube for identifying obstructive sites of the upper airway during sleep. There was no significant difference between two nights in seven obstructive sleep apnoea (OSA) patients regarding the level distribution of pharyngeal narrowings, when the pharynx was divided into two segments (retropalatal and retrolingual). We also compared the level distribution determined by magnetic resonance imaging (MRI) with the level distribution found by flextube reflectometry in seven OSA patients. There was no significant difference between flextube and MRI level distributions during obstructive events, but due to few subjects the power of the test was limited. We found a statistically significant correlation between the number of flextube narrowings per hour of sleep and the number of obstructive apnoeas and hypopnoeas per hour of sleep determined by polysomnography (PSG) in 21 subjects (Spearman's correlation coefficient r = 0.79, P < 0.001). In conclusion, the flextube reflectometry system seems to be useful for level diagnosis in OSA before and after treatment.

摘要

本研究的目的是检测一种基于柔性管内声音反射的新技术,用于识别睡眠期间上气道的阻塞部位。在七名阻塞性睡眠呼吸暂停(OSA)患者中,当将咽部分为两个节段(软腭后和舌后)时,两晚之间咽部狭窄的水平分布无显著差异。我们还比较了七名OSA患者中磁共振成像(MRI)确定的水平分布与柔性管反射测量法发现的水平分布。在阻塞事件期间,柔性管和MRI水平分布之间无显著差异,但由于受试者较少,检验效能有限。我们发现,在21名受试者中,每小时睡眠中柔性管狭窄的数量与多导睡眠图(PSG)确定的每小时睡眠中阻塞性呼吸暂停和呼吸浅慢的数量之间存在统计学显著相关性(斯皮尔曼相关系数r = 0.79,P < 0.001)。总之,柔性管反射测量系统似乎有助于OSA治疗前后的水平诊断。

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