Merchant J R, Worwa C, Porter S, Coleman J M, deRegnier R A
Children's Hospital-St Paul, St Paul, Minnesota, USA.
Pediatrics. 2001 Sep;108(3):647-52. doi: 10.1542/peds.108.3.647.
Premature infants who are discharged from intensive care nurseries are known to be at increased risk for apnea, bradycardia, and oxygen desaturation while in the upright position. These small infants also do not fit securely in standard infant car seats. Because of these problems, the American Academy of Pediatrics recommends a period of observation in a car seat for all infants who are born at <37 weeks' gestation. It is not clear whether this recommendation should apply to the minimally preterm infants (born at 35-36 weeks' gestation) who are healthy at birth and are hospitalized in the normal newborn nursery. The objective of this study was to evaluate the respiratory stability and safety requirements of healthy, minimally preterm infants in car seats compared with term infants.
Fifty healthy, nonmonitored, preterm infants (mean gestational age: 35.8 +/- 0.6 weeks) and 50 term infants (mean gestational age: 39.5 +/- 1.4 weeks) were recruited from a level I newborn nursery in a community hospital. Appropriateness of car seat fit was documented for each infant. Heart rate, respiratory rate, and pulse oximetry were evaluated while infants were supine and in their car seats. Apneic and bradycardic events were recorded in addition to a continuous recording of oxygen saturation values.
Twenty-four percent of preterm and 4% of term newborn infants did not fit securely into suitable car seats despite the use of blanket rolls. Mean oxygen saturation values declined significantly in both preterm and term infants from 97% in the supine position (range: 92%-100%) to 94% after 60 minutes in their car seats (range: 87%-100%). Seven infants (3 preterm and 4 term) had oxygen saturation values of <90% for longer than 20 minutes in their car seats. Twelve percent of the preterm infants (95% confidence interval: 4.5%-24.3%) but no term infants had apneic or bradycardic events in their car seats.
Our data support the current American Academy of Pediatrics recommendations that all infants who are born at <37 weeks' gestation, including those who are admitted to level I community hospitals, be observed for respiratory instability and secure fit in their car seats before hospital discharge. Because lowering of oxygen saturation values was seen uniformly in all newborn infants, car seats should be used only for travel, and travel should be minimized during the first months of life.
从重症监护病房出院的早产儿在直立位时发生呼吸暂停、心动过缓和氧饱和度下降的风险增加。这些小婴儿也不能牢固地适配标准婴儿汽车安全座椅。由于这些问题,美国儿科学会建议对所有孕周小于37周出生的婴儿在汽车安全座椅上进行一段时间的观察。目前尚不清楚这一建议是否应适用于出生时健康且在正常新生儿病房住院的轻度早产儿(孕35 - 36周出生)。本研究的目的是评估与足月儿相比,健康的轻度早产儿在汽车安全座椅上的呼吸稳定性和安全要求。
从一家社区医院的一级新生儿病房招募了50名健康、未进行监测的早产儿(平均孕周:35.8±0.6周)和50名足月儿(平均孕周:39.5±1.4周)。记录每个婴儿适配汽车安全座椅的情况。在婴儿仰卧位和坐在汽车安全座椅上时评估心率、呼吸频率和脉搏血氧饱和度。除了持续记录氧饱和度值外,还记录呼吸暂停和心动过缓事件。
尽管使用了毯子卷,24%的早产儿和4%的足月儿仍不能牢固地适配合适的汽车安全座椅。早产儿和足月儿的平均氧饱和度值均显著下降,从仰卧位时的97%(范围:92% - 100%)降至坐在汽车安全座椅上60分钟后的94%(范围:87% - 100%)。7名婴儿(3名早产儿和4名足月儿)在汽车安全座椅上氧饱和度值低于90%的时间超过20分钟。12%的早产儿(95%置信区间:4.5% - 24.3%)在汽车安全座椅上发生了呼吸暂停或心动过缓事件,而足月儿未发生。
我们的数据支持美国儿科学会目前的建议,即所有孕周小于37周出生的婴儿,包括入住一级社区医院的婴儿,在出院前应观察其呼吸不稳定情况以及在汽车安全座椅上的适配情况。由于所有新生儿的氧饱和度值均出现下降,汽车安全座椅仅应用于出行,并且在生命的头几个月应尽量减少出行。