Gozal D, Wang M, Pope D W
Kosair Children's Hospital Sleep Medicine and Apnea Center, Division of Pediatric Sleep Medicine, Department of Pediatrics, University of Louisville, Louisville, Kentucky 40202, USA.
Pediatrics. 2001 Sep;108(3):693-7. doi: 10.1542/peds.108.3.693.
Excessive daytime sleepiness (EDS) occurs frequently in adult patients with obstructive sleep apnea (OSA). However, the incidence of EDS in children with OSA is unknown.
To determine overall daytime sleepiness in pediatric OSA, 54 children with OSA, 14 children with primary snoring (PS), and 24 controls (C) underwent an overnight diagnostic polysomnogram followed the next day by a multiple sleep latency test.
The mean apnea index was 15.1 +/- 9.5 standard deviation in OSA, 1.1 +/- 0.5 in PS, and 0.1 +/- 0.3 in C. Mean sleep latencies were 23.7 +/- 3.0 minutes in C, 23.7 +/- 3.1 minute in PS, and 20.0 +/- 7.1 minute in OSA patients. However, only 7 children with OSA had mean sleep latencies <10 minutes. In addition, shorter sleep latencies were more likely to occur in more obese OSA patients and those with more severe apnea index, and oxyhemoglobin desaturation.
Shortened sleep latencies occur in children with OSA, but EDS is infrequent and tends to develop among more severe and/or obese patients.
阻塞性睡眠呼吸暂停（OSA）成年患者经常出现日间过度嗜睡（EDS）。然而，OSA儿童患者中EDS的发生率尚不清楚。
为了确定小儿OSA患者的总体日间嗜睡情况，54例OSA儿童、14例原发性打鼾（PS）儿童和24例对照（C）接受了夜间诊断性多导睡眠图检查，次日进行多次睡眠潜伏期测试。
OSA患者的平均呼吸暂停指数为15.1±9.5标准差，PS患者为1.1±0.5，C组为0.1±0.3。C组的平均睡眠潜伏期为23.7±3.0分钟，PS组为23.7±3.1分钟，OSA患者为20.0±7.1分钟。然而，只有7例OSA儿童的平均睡眠潜伏期<10分钟。此外，睡眠潜伏期较短更可能发生在肥胖程度更高的OSA患者以及呼吸暂停指数和氧合血红蛋白饱和度更高的患者中。
OSA儿童存在睡眠潜伏期缩短的情况，但EDS并不常见，且倾向于在病情更严重和/或肥胖的患者中出现。
