MMWR Recomm Rep. 2001 Aug 24;50(RR-15):1-46.
Several developments have fueled the renewed interest in xenotransplantation--the use of live animal cells, tissues and organs in the treatment or mitigation of human disease. The world-wide, critical shortage of human organs available for transplantation and advances in genetic engineering and in the immunology and biology of organ/tissue rejection have renewed scientists' interest in investigating xenotransplantation as a potentially promising means to treat a wide range of human disorders. This situation is highlighted by the fact that in the United States alone, 13 patients die each day waiting to receive a life-saving transplant to replace a diseased vital organ.
有几项进展激发了人们对异种移植（即在治疗或缓解人类疾病中使用活体动物细胞、组织和器官）的新兴趣。全球范围内可用于移植的人体器官严重短缺，以及基因工程、器官/组织排斥的免疫学和生物学方面的进展，使科学家们重新燃起兴趣，将异种移植作为一种治疗多种人类疾病的潜在有效手段进行研究。仅在美国，每天就有13名患者在等待接受挽救生命的移植手术以替换患病的重要器官时死亡，这一事实凸显了这种情况。
