Chu S S, Chang Y L, Lou P J
Department of Otolaryngology, National Taiwan University Hospital, Taipei, Taiwan.
J Laryngol Otol. 2001 Aug;115(8):673-5. doi: 10.1258/0022215011908595.
Primary cutaneous adenoid cystic carcinoma (PCACC) is a particularly rare variant of sweat gland carcinoma with characteristics of indolent and progressive course and high incidence of perineural invasion and local recurrence. However, regional lymph node metastasis in PCACC is exceedingly rare and its prognostic implication is unknown. Only two previous cases of recurrent scalp PCACC were reported to be associated with cervical lymph node metastases at 42 months and 20 years, respectively, after the initial treatment. We present a case of PCACC occurring in the left parotid region with regional neck lymph node metastasis in a 64-year-old man. Because the occurrence of lymph node metastasis seems to be associated with recurrent PCACC, we suggest that neck dissection may be included in the treatment for recurrent PCACC patients.
原发性皮肤腺样囊性癌（PCACC）是一种特别罕见的汗腺癌变体，具有病程惰性且进展缓慢、神经周围侵犯和局部复发发生率高的特点。然而，PCACC发生区域淋巴结转移极为罕见，其预后意义尚不清楚。之前仅有两例复发性头皮PCACC的病例报告，分别在初始治疗后42个月和20年出现颈部淋巴结转移。我们报告一例发生在64岁男性左侧腮腺区域并伴有区域颈部淋巴结转移的PCACC病例。由于淋巴结转移的发生似乎与复发性PCACC相关，我们建议复发性PCACC患者的治疗可能应包括颈部清扫术。
