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神经科学文献的知识管理:NeuroScholar系统的数据模型及基础策略

Knowledge management of the neuroscientific literature: the data model and underlying strategy of the NeuroScholar system.

作者信息

Burns G A

机构信息

Department of Neurobiology, University of Southern California, Los Angeles, CA 90089-2520, USA.

出版信息

Philos Trans R Soc Lond B Biol Sci. 2001 Aug 29;356(1412):1187-208. doi: 10.1098/rstb.2001.0909.

Abstract

This paper describes the underlying strategy and system's design of a knowledge management system for the neuroscientific literature called 'NeuroScholar'. The problem that the system is designed to address is to delineate fully the neural circuitry involved in a specific behaviour. The use of this system provides experimental neuroscientists with a new method of building computational models ('knowledge models') of the contents of the published literature. These models may provide input for analysis (conceptual or computational), or be used as constraint sets for conventional neural modelling work. The underlying problems inherent in this approach, the general framework for the proposed solution, the practical issues concerning usage of the system and a detailed, technical account of the system are described. The author uses a widely used software specification language (the Universal Modelling Language) to describe the design of the system and present examples from published work concerned with classical eyeblink conditioning in the rabbit.

摘要

本文描述了一个名为“神经学者”(NeuroScholar)的神经科学文献知识管理系统的基本策略和系统设计。该系统旨在解决的问题是全面描绘参与特定行为的神经回路。使用这个系统为实验神经科学家提供了一种新方法,用于构建已发表文献内容的计算模型(“知识模型”)。这些模型可为分析(概念性或计算性)提供输入,或用作传统神经建模工作的约束集。文中描述了这种方法所固有的潜在问题、所提出解决方案的总体框架、有关系统使用的实际问题以及该系统的详细技术说明。作者使用一种广泛使用的软件规范语言(统一建模语言)来描述系统设计,并给出了已发表的有关兔子经典眨眼条件反射研究工作的示例。

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