Schultz A L, Pardee G P, Ensinck J W
West J Med. 1975 Jul;123(1):76-80.
To determine how adequately patients who participate as subjects for clinical investigation understand their commitment, 50 patients admitted to the Clinical Research Center of the University of Washington were interviewed. Their responses were compared with the detailed statements in the consent forms for the 23 specific protocols under which they were being studied. In spite of careful controls in accord with guidelines of a review committee, only half the patients were able to describe accurately their expectations of the studies to which they had given signed consent.
为了确定参与临床研究的患者对自身所做承诺的理解程度，我们对华盛顿大学临床研究中心收治的50名患者进行了访谈。将他们的回答与针对他们所参与研究的23项具体方案的知情同意书中的详细说明进行了比较。尽管严格按照审查委员会的指导方针进行了仔细控制，但只有一半的患者能够准确描述他们对已签署同意书的研究的期望。
