Volozhin A I, Pesin R S, Lebedev V G, Popov V K, Roginskiĭ V V, Deshevoĭ Iu B
Patol Fiziol Eksp Ter. 2001 Apr-Jun(2):17-9.
The morphological composition of cells on implants made of different composition materials was studied on the model of long-term bone marrow cultures at cultivation for 28 days. Three samples of materials were investigated: polymethyl methacrylate (PMMC), PMMC with hydroxyapatite (HA) and PMMC with HA and subsequent processing with supercritical carbon dioxide. A gradual rise in total number of cells was observed on the implants for 4 weeks as well as increasing number of stromal and hemopoietic cells. With increasing time of cultivation the share of stromal cells was growing while the percent of hemopoietic cells fell. The greater number of hemopoietic cells was observed on the samples of the implants made from composites containing HA vs implants made from the initial PMMC.
在长期骨髓培养模型上，培养28天，研究了由不同成分材料制成的植入物上细胞的形态组成。研究了三种材料样本：聚甲基丙烯酸甲酯（PMMC）、含羟基磷灰石（HA）的PMMC以及含HA并随后用超临界二氧化碳处理的PMMC。在4周内观察到植入物上细胞总数逐渐增加，以及基质细胞和造血细胞数量的增加。随着培养时间的增加，基质细胞的比例在增加，而造血细胞的百分比在下降。与由初始PMMC制成的植入物相比，在由含HA的复合材料制成的植入物样本上观察到更多的造血细胞。
