Santos R, Barojas E, Alarcón-Segovia D, Ibáñez G
Am J Ophthalmol. 1975 Aug;80(2):249-52. doi: 10.1016/0002-9394(75)90140-3.
We performed complete ocular examination, including fluorescein angiography of the fundus, in 50 ambulatory patients with moderately active or inactive systemic lupus erythematosus; none had ocular symptoms. One patient had drusen and two patients had increased intraocular pressures with disk cupping attributable to orally administered corticosteroids. No patient had detectable abnormalities by ophthalmoscopic examination. Despite this apparently normal condition, fluorescein angiography revealed single or multiple microaneurysms in nine patients (13 eyes) and retinal capillary dilatations with leakage of fluorescein in six patients (six eyes). Both abnormalities occurred in two patients. These capillary changes in moderately ill patients with lupus erythematosus are probably the residue of previous acute vasculitis, perhaps due to immune-complex deposition.
我们对50例非卧床的中度活动或非活动期系统性红斑狼疮患者进行了全面的眼部检查，包括眼底荧光血管造影；这些患者均无眼部症状。1例患者有玻璃膜疣，2例患者因口服皮质类固醇导致眼压升高伴视盘杯状凹陷。通过检眼镜检查未发现患者有可检测到的异常。尽管表面情况正常，但荧光血管造影显示9例患者（13只眼）有单个或多个微动脉瘤，6例患者（6只眼）有视网膜毛细血管扩张伴荧光素渗漏。2例患者同时出现了这两种异常。狼疮中度患者的这些毛细血管变化可能是既往急性血管炎的残留表现，可能是由于免疫复合物沉积所致。
