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双相情感障碍患者子女的精神病理学患病率

Prevalence of psychopathology in children of a bipolar parent.

作者信息

Wals M, Hillegers M H, Reichart C G, Ormel J, Nolen W A, Verhulst F C

机构信息

Institute for Mental Health Care, Utrecht, The Netherlands.

出版信息

J Am Acad Child Adolesc Psychiatry. 2001 Sep;40(9):1094-102. doi: 10.1097/00004583-200109000-00019.

Abstract

OBJECTIVE

To determine psychopathology in adolescent children of a bipolar parent living in the Netherlands, using multiple sources of information (self-, parent, and teacher reports).

METHOD

Problem behavior in 140 offspring (aged 12-21 years) of 86 bipolar parents was assessed with the Child Behavior Checklist (CBCL), the Teacher's Report Form (TRF), and the Youth Self-Report (YSR) between 1997 and 1999. All adolescents, bipolar parents, and their available spouses were interviewed with the Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime Version (K-SADS-PL).

RESULTS

Higher problem scores were found for 8 of the 11 CBCL scales for girls and 4 of the 11 CBCL scales for boys, compared with a Dutch normative sample, and 1 Young Adult Self-Report (YASR) scale for girls compared with an American normative sample. Lower problem scores were found on 4 YSR and 4 YASR scales for boys, 1 TRF scale for girls, and 1 TRF scale for boys. The prevalence of current DSM-IV diagnoses in the offspring was 29% and of life-time DSM-IV diagnoses, 44%.

CONCLUSIONS

The prevalence of problem behavior and DSM-IV diagnoses found in our sample did not support the notion that the level of psychopathology in children aged 12 to 21 years of bipolar parents is highly elevated. This study, similar to prior studies, suffers from lack of information on the representativeness of the sample and a rather low response rate.

摘要

目的

利用多种信息来源(自我报告、父母报告和教师报告)确定生活在荷兰的双相情感障碍患者的青春期子女的精神病理学状况。

方法

1997年至1999年间,使用儿童行为清单(CBCL)、教师报告表(TRF)和青少年自我报告(YSR)对86名双相情感障碍患者的140名子女(年龄在12至21岁之间)的问题行为进行了评估。所有青少年、双相情感障碍患者及其配偶均接受了学龄儿童情感障碍和精神分裂症量表-目前和终生版(K-SADS-PL)的访谈。

结果

与荷兰正常样本相比,女孩的11个CBCL量表中有8个以及男孩的11个CBCL量表中有4个的问题得分更高,与美国正常样本相比,女孩的1个青年成人自我报告(YASR)量表得分更高。男孩的4个YSR量表和4个YASR量表、女孩的1个TRF量表以及男孩的1个TRF量表的问题得分较低。后代中当前DSM-IV诊断的患病率为29%,终生DSM-IV诊断的患病率为44%。

结论

我们样本中发现的问题行为和DSM-IV诊断的患病率并不支持双相情感障碍患者12至21岁子女的精神病理学水平大幅升高这一观点。与之前的研究类似,本研究存在样本代表性信息不足以及回复率较低的问题。

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