Eyre P
Am J Vet Res. 1975 Aug;36(08):1081-4.
Serotonin (5-hydroxytryptamine) contracted the pulmonary artery, trachea, and bronchus in both cattle and sheep. Serotonin contracted the calf pulmonary vein, but it relaxed the pulmonary vein of sheep. Histamine constricted the 2 pulmonary blood vessels and trachea in calves and sheep. In contrast, histamine relaxed the ovine bronchus, but not the bronchus of the calf. Antigen (equine serum) constricted pulmonary veins from sensitized calves, but relaxed pulmonary veins from similarly sensitized sheep. Apparently, sheep are naturally more resistant than calves to both histamine and serotonin which contribute to the pulmonary inflammatory reaction.
血清素（5-羟色胺）可使牛和羊的肺动脉、气管及支气管收缩。血清素可使犊牛肺静脉收缩，但使绵羊肺静脉舒张。组胺可使犊牛和绵羊的两条肺血管及气管收缩。相比之下，组胺可使绵羊支气管舒张，但不能使犊牛支气管舒张。抗原（马血清）可使致敏犊牛的肺静脉收缩，但可使同样致敏的绵羊肺静脉舒张。显然，绵羊对导致肺部炎症反应的组胺和血清素天生比犊牛更具抵抗力。
