Costill D L, Coté R, Miller E, Miller T, Wynder S
Aviat Space Environ Med. 1975 Jun;46(6):795-800.
In an attempt to determine the value of replacing sweat losses with and electrolyte solution, 12 subjects (2 women and 10 men) were dehydrated (minus 3% body weight) on 5 successive days. During one 5-d sequence, the subjects replaced fluid losses with a glucose-electrolyte solution, while water was the only fluid ingested during a second 5-d series. With the exception of the drink, daily ionic and caloric intakes were identical for the two 5-d conditions. Measurements of water and electrolyte losses in sweat and urine showed a positive balance in body Na+, K+, and Cl- during both the water (W) and electrolyte solution (ES) treatments. Subjects accumulated significantly more Na+ during the W experiments (392 mEq/5 d) than when the electrolyte solution was ingested (334 mEq/5 d). As a result, the extracellular fluid compartment, represented by plasma volume, increased 12.2 and 9.0% during the 5-d sequence of the W and ES trials, respectively. It was concluded that the addition of electrolytes to drinking water is of minimal value for subjects who dehydrated (-3%) on repeated days and are permitted to ingest food and drink libitum
为了确定用电解质溶液补充汗液流失的价值,12名受试者(2名女性和10名男性)连续5天进行脱水(体重减轻3%)。在一个5天的时间段内,受试者用葡萄糖电解质溶液补充液体流失,而在第二个5天的时间段内,仅摄入水作为唯一的液体。除饮品外,两种5天情况的每日离子和热量摄入相同。对汗液和尿液中的水和电解质流失进行测量,结果显示在水(W)处理和电解质溶液(ES)处理期间,机体的钠、钾和氯均呈正平衡。与摄入电解质溶液时相比(334 mEq/5天),受试者在W实验期间积累了更多的钠(392 mEq/5天)。因此,以血浆量为代表的细胞外液在W试验和ES试验的5天期间分别增加了12.2%和9.0%。得出的结论是,对于连续多日脱水(-3%)且允许随意摄入食物和饮品的受试者而言,在饮用水中添加电解质的价值极小。