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长期给予长叶马钱子后对非交配雄性大鼠的壮阳作用评估

Aphrodisiac evaluation in non-copulator male rats after chronic administration of Eurycoma longifolia Jack.

作者信息

Ang H H, Ngai T H

机构信息

School of Pharmaceutical Sciences, University of Science Malaysia, Minden, 11800, Penang, Malaysia.

出版信息

Fundam Clin Pharmacol. 2001 Aug;15(4):265-8. doi: 10.1046/j.1472-8206.2001.00038.x.

Abstract

The aphrodisiac effect of Eurycoma longifolia Jack (0.5 g/kg) was evaluated in noncopulator male rats using an electrical cage. Fractions of E. longifolia Jack decreased the hesitation time of noncopulator male rats, throughout the investigation period. Furthermore, it possessed a transient increase in the percentage of the male rats responding to the right choice, more than 50% of the male rats scored "right choice" after 3 weeks post-treatment and the effect became more prominent after 8 weeks post-treatment (only 40-50% of the control male rats responded to the right choice) using the electrical copulation cage. Hence, this study lends further support to the use of the plant by indigenous populations as a traditional medicine for its aphrodisiac property.

摘要

使用电笼对未交配的雄性大鼠评估了长叶刺蒺藜(0.5克/千克)的壮阳效果。在整个研究期间,长叶刺蒺藜提取物缩短了未交配雄性大鼠的犹豫时间。此外,它使做出正确选择的雄性大鼠百分比出现短暂增加,使用电交配笼,在治疗后3周,超过50%的雄性大鼠做出了“正确选择”,且在治疗后8周效果变得更加显著(对照组雄性大鼠只有40%-50%做出正确选择)。因此,本研究进一步支持了当地居民将该植物作为具有壮阳特性的传统药物使用。

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