Chauhan Nagendra Singh, Sharma Vikas, Dixit V K, Thakur Mayank
Department of Pharmaceutical Sciences, Dr. Harisingh Gour Central University, Sagar, Madhya Pradesh 470003, India ; Drugs Testing Laboratory Avam Anusandhan Kendra, GE Road, Raipur, Chhattisgarh 492010, India.
Department of Pharmaceutical Sciences, Dr. Harisingh Gour Central University, Sagar, Madhya Pradesh 470003, India.
Biomed Res Int. 2014;2014:868062. doi: 10.1155/2014/868062. Epub 2014 Aug 18.
The use of plant or plant-based products to stimulate sexual desire and to enhance performance and enjoyment is almost as old as the human race itself. The present paper reviews the active, natural principles, and crude extracts of plants, which have been useful in sexual disorders, have potential for improving sexual behaviour and performance, and are helpful in spermatogenesis and reproduction. Review of refereed journals and scientific literature available in electronic databases and traditional literature available in India was extensively performed. The work reviews correlation of the evidence with traditional claims, elucidation, and evaluation of a plausible concept governing the usage of plants as aphrodisiac in total. Phytoconstituents with known structures have been classified in appropriate chemical groups and the active crude extracts have been tabulated. Data on their pharmacological activity, mechanism of action, and toxicity are reported. The present review provides an overview of the herbs and their active molecule with claims for improvement of sexual behaviour. A number of herbal drugs have been validated for their effect on sexual behavior and fertility and can therefore serve as basis for the identification of new chemical leads useful in sexual and erectile dysfunction.
利用植物或植物制品来刺激性欲、提高性能力和性快感,几乎与人类本身的历史一样悠久。本文综述了对性功能障碍有益、具有改善性行为和性能力的潜力且有助于精子发生和生殖的植物活性天然成分及粗提物。广泛查阅了电子数据库中的同行评审期刊和科学文献以及印度的传统文献。该研究综述了证据与传统说法的相关性,阐明并评估了一个关于植物作为壮阳药使用的合理概念。具有已知结构的植物成分已被归类到适当的化学类别中,活性粗提物已被制成表格。报告了它们的药理活性、作用机制和毒性数据。本综述概述了声称可改善性行为的草药及其活性分子。许多草药对性行为和生育能力的影响已得到验证,因此可为鉴定对性功能障碍和勃起功能障碍有用的新化学先导物提供依据。