马立克氏病淋巴瘤淋巴母细胞系的超微结构

Frazier J A, Powell P C

Br J Cancer. 1975 Jan;31(1):7-14. doi: 10.1038/bjc.1975.2.

The ultrastructure of two lymphoblastoid cell lines derived from Marek's disease lymphomata has been studied. The cells varied from 5 to 12 mum in diameter and had large round or oval nuclei. A nucleolus was occasionally present and about 3% of cells showed projections of the nuclear envelope. The cytoplasm contained many ribosomes and several mitochondria but endoplasmic reticulum was sparse. A small number of cells contained annulate lamellae and crystalline structures were occasionally seen. Cells with immature intranuclear herpesvirus particles were rarely present. The cells had many ultrastructural features in common with Burkitt's lymphoma-derived cell lines.

对源自马立克氏病淋巴瘤的两个淋巴母细胞样细胞系的超微结构进行了研究。细胞直径为5至12微米，具有大的圆形或椭圆形细胞核。偶尔有一个核仁，约3%的细胞显示核膜突起。细胞质含有许多核糖体和几个线粒体，但内质网稀疏。少数细胞含有环状片层，偶尔可见晶体结构。含有未成熟核内疱疹病毒颗粒的细胞很少见。这些细胞具有许多与源自伯基特淋巴瘤的细胞系共有的超微结构特征。