Müller R, Willers H, Knocke K W, Sipos S, Höpken W
Dtsch Med Wochenschr. 1979 Oct 19;104(42):1471-4. doi: 10.1055/s-0028-1129124.
The frequency of non-A, non-B hepatitis (n = 325) was determined among all cases (n = 1368) of acute viral hepatitis observed in the Hannover are abetwen 1975 and 1978. Hepatitis A was excluded by demonstration of anti-HAV-IgM, hepatitis B by demonstration of HBs antigen or an isolated occurrence of anti-HBc at the beginning of the disease. Non-A, non-B hepatitis occurred predominantly in adults and showed no seasonal variability. As a consequence of results of followup investigations in 174 hepatitis patients 2 years after the onset of the disease it can be assumed that non-A, non-B hepatitis tends to lead to chronic courses more frequently than hepatitis B.
在1975年至1978年期间于汉诺威地区观察到的所有1368例急性病毒性肝炎病例中,确定了非甲非乙型肝炎的发病频率(n = 325)。通过检测抗甲型肝炎病毒免疫球蛋白M排除甲型肝炎,通过检测乙型肝炎表面抗原或在疾病初期单独出现的抗乙型肝炎核心抗体排除乙型肝炎。非甲非乙型肝炎主要发生在成年人中,且无季节性变化。根据对174例肝炎患者在疾病发作两年后的随访调查结果,可以认为非甲非乙型肝炎比乙型肝炎更易导致慢性病程。