McLaren M J, Lachman A S, Barlow J B
Br Heart J. 1979 May;41(5):554-8. doi: 10.1136/hrt.41.5.554.
A survey conducted by cardiologists in Soweto, Johannesburg, provided an opportunity of assessing the frequency of congenital heart disease in black schoolchildren. Among 12,050 schoolchildren aged 2 to 18 years, 48 had a congenital heart defect, yielding a prevalence of 3.9 per 1000. Only in 2- to 6-year-old children did the prevalence exceed that of rheumatic heart disease. The distribution of the types of defects was largely similar to that reported in other surveys with a predominance (52%) of ventricular septal defects. Two unusual findings were the unexplained absence of persistent ductus arteriosus in these children, and the detection of 5 children with situs inversus (1 in 2410). In all but one child, the congenital heart defect was first discovered during the survey. Despite the limitations of a prevalence study, it can be concluded that congenital heart disease is at least as common in this South African black community as in Caucasians.
约翰内斯堡索韦托的心脏病专家开展的一项调查,提供了评估黑人学童先天性心脏病发病频率的机会。在12050名2至18岁的学童中,有48人患有先天性心脏缺陷,患病率为每1000人中有3.9人。只有在2至6岁的儿童中,先天性心脏病的患病率超过了风湿性心脏病。缺陷类型的分布与其他调查报道的情况大致相似,以室间隔缺损为主(占52%)。有两个不寻常的发现:这些儿童中不明原因地没有动脉导管未闭,以及检测到5例内脏反位的儿童(每2410人中有1例)。除1名儿童外,所有先天性心脏缺陷都是在调查期间首次发现的。尽管患病率研究存在局限性,但可以得出结论,先天性心脏病在这个南非黑人社区至少与在白种人中一样常见。