Salgueiro M J, Krebs N, Zubillaga M B, Weill R, Postaire E, Lysionek A E, Caro R A, De Paoli T, Hager A, Boccio J
Radioisotope Laboratory, School of Pharmacy and Biochemistry, University of Buenos Aires, Piso Bajo, Argentina.
Biol Trace Elem Res. 2001 Sep;81(3):215-28. doi: 10.1385/BTER:81:3:215.
Diabetes mellitus is a group of metabolic disorders, the incidence of which varies widely throughout the world. The treatment of diabetes mellitus includes insulin, oral antidiabetic agents, and dietary regimens. Although the emphasis is on macronutrients intakes, there is strong evidence that there is an abnormal metabolism of several micronutrients in diabetic individuals. Zinc is one of the essential micronutrients of which status and metabolism is altered in this condition. This work is a short review about the close relation among zinc, glucose metabolism, and insulin physiology, as well as about the few experimental data about zinc absorption and zinc supplementation in diabetes mellitus patients.
糖尿病是一组代谢紊乱疾病，其发病率在全球范围内差异很大。糖尿病的治疗包括胰岛素、口服抗糖尿病药物和饮食方案。虽然重点是宏量营养素的摄入，但有强有力的证据表明糖尿病患者体内几种微量营养素存在代谢异常。锌是一种必需的微量营养素，在这种情况下其状态和代谢会发生改变。这项工作是一篇简短的综述，内容涉及锌、葡萄糖代谢和胰岛素生理学之间的密切关系，以及关于糖尿病患者锌吸收和补锌的少量实验数据。
