Ellepola A N, Samaranayake L P
Oral Bio-sciences, Faculty of Dentistry, University of Hong Kong, SAR.
Oral Dis. 2001 Jul;7(4):211-6.
Candidosis is by far the commonest oral fungal infection in man and could manifest as an adverse effect of drug therapy such as inhaled or topically applied corticosteroids. Due to the anti-inflammatory and immunosuppressive effect steroids are used in the management of bronchial asthma and oral mucosal diseases. In this mini review we discuss the clinical and laboratory findings on the relationship between steroid inhalers, other topical steroids and oral candidosis, possible mechanisms of pathogenicity following such therapy as well as the precautions that could be taken to minimize this adverse side effect.
念珠菌病是目前人类最常见的口腔真菌感染，可能表现为药物治疗的不良反应，如吸入或局部应用皮质类固醇。由于具有抗炎和免疫抑制作用，类固醇被用于治疗支气管哮喘和口腔黏膜疾病。在这篇小型综述中，我们讨论了类固醇吸入器、其他局部类固醇与口腔念珠菌病之间关系的临床和实验室研究结果，此类治疗后可能的致病机制，以及为尽量减少这种不良反应可采取的预防措施。
