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内脏利什曼病(黑热病),不仅在热带地区是一种重要疾病(作者译)

[Visceral leishmaniasis (kala-azar), an important disease not only in the tropics (author's transl)].

作者信息

Gottstein U, Steiner K, Hauk H, Klimaschewski G, Sedlmeyer I

出版信息

Dtsch Med Wochenschr. 1975 Oct 3;100(40):2022, 2025-7. doi: 10.1055/s-0028-1106495.

Abstract

A 39-year-old woman contracted visceral leishmaniasis on a 14-day visit to southern Italy and died of staphylococcal septicaemia before specific treatment could be effective, diagnostic efforts over four months having failed to make the diagnosis until four weeks before death. Eight further cases reported in German-speaking medical journals illustrate similar diagnostic difficulties. The disease is accompanied by septic temperatures, frequently with two daily spikes, hepato- and splenomegaly, normochromic anaemia and leucocytopenia. But diagnosis can only be made by specific tests. The organisms can be discovered in sternal puncture and organ biopsies only if the Giemsa stain is used. Complement-fixation reaction for leishmania should be tried repeatedly, in case the disease is suspected.

摘要

一名39岁女性在访问意大利南部的14天期间感染了内脏利什曼病,在特异性治疗生效前死于葡萄球菌败血症,长达四个月的诊断工作一直未能确诊,直到死亡前四周才得以诊断。德语医学期刊报道的另外八例病例也说明了类似的诊断困难。该疾病伴有败血症热型,通常每天有两次体温高峰,肝脾肿大,正色素性贫血和白细胞减少。但只有通过特异性检测才能做出诊断。只有使用吉姆萨染色,才能在胸骨穿刺和器官活检中发现病原体。如果怀疑患有该病,应反复进行利什曼原虫补体结合反应检测。

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