父母酗酒或吸毒与儿童行为抑制之间不存在关联。
Lack of association between parental alcohol or drug addiction and behavioral inhibition in children.
作者信息
Biederman J, Hirshfeld-Becker D R, Rosenbaum J F, Perenick S G, Wood J, Faraone S V
机构信息
Department of Psychiatry Unit of Clinical Psychopharmacology, Massachusetts General Hospital, Boston, 02114, USA.
出版信息
Am J Psychiatry. 2001 Oct;158(10):1731-3. doi: 10.1176/appi.ajp.158.10.1731.
OBJECTIVE
"Behavioral inhibition to the unfamiliar" has been proposed as a precursor to anxiety. A recent study proposed that it may also be a precursor to alcoholism. The authors sought to replicate the latter finding through a secondary analysis of data from a large study of young children (age 2-6 years)-offspring of parents with panic and depressive disorders-who had been assessed for behavioral inhibition through laboratory-based observations.
METHOD
The offspring were stratified on the basis of presence or absence of parental lifetime history of DSM-III-R alcohol dependence (N=115 versus N=166, respectively) or drug dependence (N=78 versus N=203). The rates of behavioral inhibition were then compared between groups.
RESULTS
Despite adequate power to detect associations, neither parental alcohol dependence nor drug dependence was associated with a higher risk for behavioral inhibition in the offspring.
CONCLUSIONS
These results are not consistent with the hypothesis linking behavioral inhibition to addictions.
目的
“对不熟悉事物的行为抑制”被认为是焦虑的先兆。最近一项研究提出，它也可能是酗酒的先兆。作者试图通过对一项针对幼儿（2至6岁）的大型研究数据进行二次分析来重现后一项发现，这些幼儿是患有惊恐和抑郁症的父母的后代，他们通过基于实验室的观察对行为抑制进行了评估。
方法
根据父母是否有DSM-III-R酒精依赖（分别为N = 115和N = 166）或药物依赖（N = 78和N = 203）的终生病史对后代进行分层。然后比较各组之间的行为抑制率。
结果
尽管有足够的能力检测关联，但父母的酒精依赖和药物依赖均与后代行为抑制的较高风险无关。
结论
这些结果与将行为抑制与成瘾联系起来的假设不一致。
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