Weinberg A G, Kirkpatrick J B
Dev Med Child Neurol. 1975 Aug;17(4):511-6. doi: 10.1111/j.1469-8749.1975.tb03503.x.
The case of an infant with Werding-Hoffmann disease, who died at the age of 4 1/2 days, is reported. At autopsy there was severe cerebellar hypoplasia, associated with degenerative changes in the brain-stem nuclei. This case supports the concept that cerebellar hypoplasia may develop as a manifestation of the neuronal abiotrophy of Werdnig-Hoffmann disease. A similarity has been noted between the cerebellar lesion found in the child reported here and that produced by viral infection in experimental animals.
报告了一例患有韦尔登-霍夫曼病的婴儿病例，该婴儿在4.5日龄时死亡。尸检发现有严重的小脑发育不全，并伴有脑干核的退行性改变。该病例支持小脑发育不全可能作为韦尔登-霍夫曼病神经元性生命活力缺失的一种表现而发生的观点。已注意到这里报告的儿童小脑病变与实验动物病毒感染所产生的病变之间存在相似性。
