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[疟疾流行地区疟疾发作的诊断:理论层面与实际意义]

[Diagnosis of malaria attacks in endemic areas: theoretical aspects and practical implications].

作者信息

Rogier C, Henry M C, Spiegel A

机构信息

Unité de Parasitologie, IMTSSA, 13998 Marseille Armées, France.

出版信息

Med Trop (Mars). 2001;61(1):27-46.

Abstract

What criteria can be used to diagnose malaria in health centers located in endemic areas? Can an algorithm be developed for management of fever episodes? What parameters should be used to assess the morbidity of malaria for public health surveys or for studies to determine the efficacy insecticide-impregnated bednets, drug prophylaxis protocols, or anti-malarial vaccinations? Finding a useful definition for malaria attack is a perennial problem that becomes more difficult to resolve as the transmission rate and immunity level of the population increases. This review presents the fundamental aspects of diagnosing malaria. The choice of diagnostic technique requires knowledge of physiopathological, epidemiological, and clinical features. There is no single method. It depends on the circumstances, epidemiological context, available facilities, and goals. Diagnosis for treatment is one thing. Diagnosis for evaluation is another. In addition to discussing these concepts, this article provides references from the recent literature and up-to-date information needed to deal with the problem of diagnosing malaria attacks in endemic areas.

摘要

在疟疾流行地区的卫生中心,可以使用哪些标准来诊断疟疾?能否开发一种算法来管理发热病例?在公共卫生调查或确定杀虫剂处理过的蚊帐、药物预防方案或抗疟疾疫苗接种效果的研究中,应该使用哪些参数来评估疟疾的发病率?找到一个有用的疟疾发作定义是一个长期存在的问题,随着人群传播率和免疫力水平的提高,这个问题变得越来越难以解决。本综述介绍了诊断疟疾的基本方面。诊断技术的选择需要了解生理病理学、流行病学和临床特征。没有单一的方法。这取决于具体情况、流行病学背景、可用设施和目标。用于治疗的诊断是一回事。用于评估的诊断是另一回事。除了讨论这些概念之外,本文还提供了近期文献的参考文献以及处理疟疾流行地区疟疾发作诊断问题所需的最新信息。

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