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患有佝偻病婴儿的母亲体内维生素D缺乏。

Vitamin D deficiency in mothers of infants with rickets.

作者信息

Nozza J M, Rodda C P

机构信息

Department of Paediatrics, Monash University, Monash Medical Centre, Melbourne, VIC.

出版信息

Med J Aust. 2001 Sep 3;175(5):253-5. doi: 10.5694/j.1326-5377.2001.tb143559.x.

DOI:10.5694/j.1326-5377.2001.tb143559.x
PMID:11587256
Abstract

OBJECTIVE

To identify infants treated for vitamin D deficiency rickets, and to determine the incidence of vitamin D deficiency in their mothers and their mothers' country of origin.

DESIGN

A retrospective audit of the medical records of children diagnosed with vitamin D deficiency rickets. Inpatients were identified by discharge diagnoses of vitamin D deficiency or hypocalcaemia and outpatients by pharmacy dispensing of cholecalciferol.

SETTING

The Women's and Children's Health Care Network and the Southern Health Care Network (Melbourne, VIC) from June 1994 to February 1999.

PATIENTS

55 children with vitamin D deficiency rickets.

RESULTS

Fifty-four of the 55 children were born to mothers with ethnocultural risk factors for vitamin D deficiency. Vitamin D status had been assessed in 31 of the 55 mothers (56%): 25 (81%) had 25-hydroxyvitamin D3 concentrations < or = 25 nmol/L, consistent with osteomalacia.

CONCLUSION

Vitamin D deficiency continues to occur in children of migrant families. When infants are diagnosed with vitamin D deficiency, vitamin D levels in their mothers and siblings should also be assessed.

摘要

目的

确定接受维生素D缺乏性佝偻病治疗的婴儿,并确定其母亲维生素D缺乏的发生率及其母亲的原籍国。

设计

对诊断为维生素D缺乏性佝偻病的儿童病历进行回顾性审计。住院患者通过维生素D缺乏或低钙血症的出院诊断来确定,门诊患者通过药房发放胆钙化醇来确定。

地点

1994年6月至1999年2月期间的妇女和儿童保健网络以及南部保健网络(维多利亚州墨尔本)。

患者

55名维生素D缺乏性佝偻病儿童。

结果

55名儿童中有54名的母亲具有维生素D缺乏的种族文化风险因素。55名母亲中有31名(56%)的维生素D状况得到评估:25名(81%)的25-羟基维生素D3浓度≤25 nmol/L,符合骨软化症。

结论

移民家庭的儿童中维生素D缺乏仍有发生。当婴儿被诊断为维生素D缺乏时,也应评估其母亲和兄弟姐妹的维生素D水平。

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