Pillow J J, Forrest P J, Rodda C P
Newborn Services, Monash Medical Centre, Clayton, Victoria, Australia.
J Paediatr Child Health. 1995 Jun;31(3):180-4. doi: 10.1111/j.1440-1754.1995.tb00781.x.
To determine the current modes of presentation for the development of nutritional vitamin D deficiency in Melbourne children.
A retrospective descriptive review was undertaken of the case records of children less than 5 years of age discharged from three Melbourne hospitals with a diagnosis of vitamin D deficiency or hypocalcaemia from January 1992 to January 1994.
The study identified 13 infants and young children whose hospital admission was related to nutritional vitamin D deficiency. Significant morbidity and a broad spectrum of biochemical and clinical features were noted at presentation. All children had migrant parents and were either exclusively or predominantly breast fed. Ten infants (77%) were less than 1 year at presentation. Associated deficiencies of iron and B12 were present in five cases. Of the five mothers tested, serum 25-hydroxy vitamin D3 was low in four.
Nutritional vitamin D deficiency is a continuing health problem in infants and young children born to migrant parents living in Melbourne. Paediatricians, obstetricians and general practitioners, particularly those managing women and infants from migrant communities, should be aware of this condition. Vitamin D supplementation to high-risk women during pregnancy and to their infants should be considered.
确定墨尔本儿童营养性维生素D缺乏症发展的当前表现模式。
对1992年1月至1994年1月从墨尔本三家医院出院的5岁以下诊断为维生素D缺乏或低钙血症的儿童病例记录进行回顾性描述性研究。
该研究确定了13名婴幼儿，其住院与营养性维生素D缺乏有关。就诊时发现有明显的发病率以及广泛的生化和临床特征。所有儿童的父母均为移民，且均为纯母乳喂养或主要为母乳喂养。10名婴儿（77%）就诊时年龄小于1岁。5例存在铁和维生素B12的相关缺乏。在接受检测的5名母亲中，4名母亲的血清25-羟维生素D3水平较低。
营养性维生素D缺乏是居住在墨尔本的移民父母所生婴幼儿中持续存在的健康问题。儿科医生、产科医生和全科医生，尤其是那些为移民社区的妇女和婴儿提供治疗的医生，应了解这种情况。应考虑在孕期对高危妇女及其婴儿补充维生素D。
