Schwarz G R, Jeffs R D
J Urol. 1975 Aug;114(2):285-8. doi: 10.1016/s0022-5347(17)67009-5.
A 2 to 16-year followup of 96 ileal conduit urinary diversions in children is discussed. To assess the effect of time on renal function and structure we divided the patients into recent and remote operative groups. Patients with a longer followup (average 11.3 years) had a significantly greater incidence of pyelographic deterioration, particularly from preoperative normal status, compared to patients in the short followup group (average 4.5 years). Preoperative pyelonephritis was associated with a small but significant percentage of patients who progressed to poor renal function. Three potentially preventable and correctable late complications--stomal stenosis, excessive conduit length and ureteroileal obstruction--were associated with significant long-term deterioration in either renal function or pyelographic appearance. By using ileal conduit urinary diversion in children we attempt to provide a lifelong solution to urologic and social problems. The pyelographic deterioration rates would suggest that the solution is not perfect. Alternative forms of treatment need similar assessment for comparison. Patients who have ileal conduit urinary diversion need vigilant lifelong followup with accurate assessment of renal function, infection and pyelographic status to prevent or arrest renal deterioration.
本文讨论了对96例儿童回肠代膀胱尿流改道术进行的2至16年随访情况。为评估时间对肾功能和结构的影响,我们将患者分为近期手术组和远期手术组。与短期随访组(平均4.5年)的患者相比,随访时间较长(平均11.3年)的患者肾盂造影恶化的发生率显著更高,尤其是从术前正常状态开始恶化的情况。术前肾盂肾炎与一小部分进展为肾功能不佳的患者相关。三种潜在可预防和可纠正的晚期并发症——造口狭窄、导管过长和输尿管回肠梗阻——与肾功能或肾盂造影表现的显著长期恶化相关。通过在儿童中使用回肠代膀胱尿流改道术,我们试图为泌尿系统和社会问题提供一个终身解决方案。肾盂造影恶化率表明这个解决方案并不完美。其他治疗方式需要进行类似评估以作比较。接受回肠代膀胱尿流改道术的患者需要进行终身密切随访,并准确评估肾功能、感染情况和肾盂造影状态,以预防或阻止肾功能恶化。