拟南芥中热休克蛋白70（Hsp70）超家族的基因组分析。
Genomic analysis of the Hsp70 superfamily in Arabidopsis thaliana.
作者信息
Lin B L, Wang J S, Liu H C, Chen R W, Meyer Y, Barakat A, Delseny M
机构信息
Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan, Republic of China.
出版信息
Cell Stress Chaperones. 2001 Jul;6(3):201-8. doi: 10.1379/1466-1268(2001)006<0201:gaoths>2.0.co;2.
Abstract
The Arabidopsis genome contains at least 18 genes encoding members of the 70-kilodalton heat shock protein (Hsp70) family, 14 in the DnaK subfamily and 4 in the Hsp110/SSE subfamily. While the Hsp70s are highly conserved, a phylogenetic analysis including all members of this family in Arabidopsis and in yeast indicates the homology of Hsp70s in the subgroups, such as those predicted to localize in the same subcellular compartment and those similar to the mammalian Hsp110 and Grp170. Gene structure and genome organization suggest duplication in the origin of some genes. The Arabidopsis hsp70s exhibit distinct expression profiles; representative genes of the subgroups are expressed at relatively high levels during specific developmental stages and under thermal stress.
摘要
拟南芥基因组至少包含18个编码70千道尔顿热休克蛋白（Hsp70）家族成员的基因，其中14个属于DnaK亚家族，4个属于Hsp110/SSE亚家族。虽然Hsp70高度保守，但对拟南芥和酵母中该家族所有成员进行的系统发育分析表明，亚组中的Hsp70具有同源性，例如那些预测定位于同一亚细胞区室的成员以及与哺乳动物Hsp110和Grp170相似的成员。基因结构和基因组组织表明一些基因在起源上存在重复。拟南芥的hsp70表现出不同的表达模式；亚组的代表性基因在特定发育阶段和热胁迫下表达水平相对较高。
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本文引用的文献
1
Molecular chaperones: towards a characterization of the heat-shock protein 70 family.分子伴侣：向着热休克蛋白 70 家族的特征化研究。
Trends Cell Biol. 1997 Mar;7(3):129-33. doi: 10.1016/S0962-8924(96)10056-8.
2
The hsp110 and Grp1 70 stress proteins: newly recognized relatives of the Hsp70s.热休克蛋白110和葡萄糖调节蛋白70应激蛋白：热休克蛋白70家族新发现的亲属
Cell Stress Chaperones. 2000 Oct;5(4):276-90. doi: 10.1379/1466-1268(2000)005<0276:thagsp>2.0.co;2.
3
Extensive duplication and reshuffling in the Arabidopsis genome.拟南芥基因组中的广泛重复和重排。
Plant Cell. 2000 Jul;12(7):1093-101. doi: 10.1105/tpc.12.7.1093.
4
Protein sorting signals and prediction of subcellular localization.蛋白质分选信号与亚细胞定位预测
Adv Protein Chem. 2000;54:277-344. doi: 10.1016/s0065-3233(00)54009-1.
5
The expression of small heat shock proteins in seeds responds to discrete developmental signals and suggests a general protective role in desiccation tolerance.种子中小热激蛋白的表达对离散的发育信号作出响应，并表明其在耐干燥性方面具有普遍的保护作用。
Plant Physiol. 2000 Apr;122(4):1099-108. doi: 10.1104/pp.122.4.1099.
6
Roles of molecular chaperones in cytoplasmic protein folding.分子伴侣在细胞质蛋白折叠中的作用。
Semin Cell Dev Biol. 2000 Feb;11(1):15-25. doi: 10.1006/scdb.1999.0347.
7
Stress genes and proteins in the archaea.古生菌中的应激基因与蛋白质。
Microbiol Mol Biol Rev. 1999 Dec;63(4):923-67, table of contents. doi: 10.1128/MMBR.63.4.923-967.1999.
8
Heat shock protein 70 family: multiple sequence comparisons, function, and evolution.热休克蛋白70家族：多序列比较、功能与进化
J Mol Evol. 1998 Nov;47(5):565-77. doi: 10.1007/pl00006413.
9
Regulation of the heat-shock response.热休克反应的调控
Plant Physiol. 1998 Aug;117(4):1135-41. doi: 10.1104/pp.117.4.1135.
10
Prediction of complete gene structures in human genomic DNA.人类基因组DNA中完整基因结构的预测。
J Mol Biol. 1997 Apr 25;268(1):78-94. doi: 10.1006/jmbi.1997.0951.
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