Lin B L, Wang J S, Liu H C, Chen R W, Meyer Y, Barakat A, Delseny M
Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan, Republic of China.
Cell Stress Chaperones. 2001 Jul;6(3):201-8. doi: 10.1379/1466-1268(2001)006<0201:gaoths>2.0.co;2.
The Arabidopsis genome contains at least 18 genes encoding members of the 70-kilodalton heat shock protein (Hsp70) family, 14 in the DnaK subfamily and 4 in the Hsp110/SSE subfamily. While the Hsp70s are highly conserved, a phylogenetic analysis including all members of this family in Arabidopsis and in yeast indicates the homology of Hsp70s in the subgroups, such as those predicted to localize in the same subcellular compartment and those similar to the mammalian Hsp110 and Grp170. Gene structure and genome organization suggest duplication in the origin of some genes. The Arabidopsis hsp70s exhibit distinct expression profiles; representative genes of the subgroups are expressed at relatively high levels during specific developmental stages and under thermal stress.
拟南芥基因组至少包含18个编码70千道尔顿热休克蛋白（Hsp70）家族成员的基因，其中14个属于DnaK亚家族，4个属于Hsp110/SSE亚家族。虽然Hsp70高度保守，但对拟南芥和酵母中该家族所有成员进行的系统发育分析表明，亚组中的Hsp70具有同源性，例如那些预测定位于同一亚细胞区室的成员以及与哺乳动物Hsp110和Grp170相似的成员。基因结构和基因组组织表明一些基因在起源上存在重复。拟南芥的hsp70表现出不同的表达模式；亚组的代表性基因在特定发育阶段和热胁迫下表达水平相对较高。
