Weibel R E, Buynak E B, McLean A A, Hilleman M R
Pediatrics. 1975 Sep;56(3):380-7.
Antibody in human subjects persisted without substantial decline for 8 years after mumps vaccine (Jeryl Lynn), for 6 years after measles (Attenuvax), for 5 1/2 years after rubella vaccine (HPV-77 duck), for 5 years after measles-mumps-rubella and mumps-rubella combined vaccines, for 4 years after measles and rubella, and for 2 years after measles-mumps vaccines, the longest periods tested. Protective immunity against mumps illness persisted through the eighth year. The patterns for antibody following vaccination parallel those for natural infection and indicate that immunity will be lasting. Subclinical reinfection evidenced by antibody increase was commonly seen in persons who had been vaccinated, much as follows the natural infection.
在人体中，接种腮腺炎疫苗（杰里尔·林恩株）后抗体持续8年无显著下降，接种麻疹疫苗（减毒活疫苗）后持续6年，接种风疹疫苗（HPV - 77鸭胚株）后持续5.5年，接种麻疹 - 腮腺炎 - 风疹联合疫苗及腮腺炎 - 风疹联合疫苗后持续5年，接种麻疹和风疹疫苗后持续4年，接种麻疹 - 腮腺炎疫苗后持续2年，这是所测试的最长时间。针对腮腺炎疾病的保护性免疫持续到第八年。接种疫苗后抗体的变化模式与自然感染相似，表明免疫力将是持久的。抗体增加所证明的亚临床再感染在接种过疫苗的人群中很常见，与自然感染后的情况非常相似。
