Kilburn K H, McKenzie W
Science. 1975 Aug 22;189(4203):634-7. doi: 10.1126/science.1162344.
After hamsters had breathed fresh cigarette smoke in a miniature chamber, airways of the lung showed recruitment of polymorphonuclear leukocytes. Exposure to particles alone by removal of the vapor phase with charcoal did not change the leukocyte response. However, exposure to cigarette smoke vapor after removal of particles with Cambridge filters did not recruit leukocytes but produced nuclear and cytoplasmic vacuoles, double nuclei, and exfoliation of cells.
仓鼠在微型舱内吸入新鲜香烟烟雾后，肺部气道出现多形核白细胞募集。通过用木炭去除气相单独暴露于颗粒不会改变白细胞反应。然而，用剑桥滤器去除颗粒后暴露于香烟烟雾气相不会募集白细胞，但会产生核和细胞质空泡、双核以及细胞脱落。
