Cystoid macular edema associated with topically applied epinephrine in aphakic eyes.

A 69-year-old man with bilateral open-angle glaucoma and nonfiltering iridencleisis scars underwent combined cataract extraction and glaucoma filtering operations in each eye. Later, he again required intensive medical therapy including topically applied echothiophate iodide, epinephrine, and acetazolamide to control his glaucoma. Topical instillation of epinephrine repeatedly resulted in reversible cystoid macular edema in each eye. The macular changes were documented by fluorescein angiography. The clinical and angiographic features of the macular edema in this patient did not differ from cystoid macular edema seen in other ocular conditions.