16,（16）-二甲基前列腺素E2和不饱和脂肪酸对淋巴细胞转化的抑制作用。
Suppression of lymphocyte transformation by 16, (16) dimethyl prostaglandin E2 and unsaturated fatty acids.
作者信息
Mihas A A, Gibson R G, Hirschowitz B I
出版信息
Proc Soc Exp Biol Med. 1975 Sep;149(4):1026-8. doi: 10.3181/00379727-149-38949.
PMID:1166069
Abstract
A new synthetic prostaglandin (16, 16-PGE2) and unsaturated fatty acids have been shown to inhibit the incorporation of [3H]thymidine in the lymphocyte transformation reaction in response to phytohemagglutinin (PHA). This inhibition was not due to toxicity of these substances, for the lymphocytes remained intact and capable of excluding trypan blue.
摘要
一种新的合成前列腺素（16,16 - 前列腺素E2）和不饱和脂肪酸已被证明能抑制淋巴细胞在对植物血凝素（PHA）反应的转化反应中[3H]胸腺嘧啶核苷的掺入。这种抑制并非由于这些物质的毒性，因为淋巴细胞保持完整且能够排斥台盼蓝。
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