Zhdanov V M, Mazurenko N N, Bukrinskaia A G, Volkova M Ia, Kosiakova N P
Vopr Onkol. 1975;21(8):64-8.
The authors investigated five cell cultures producing oncornaviruses type D by the method of molecular hybridization of viral nucleic acids with cell nucleic acids. It was shown that nuclear DNA of the cell lines under study contained scores and hundreds of viral RNA genome-equivalents, while cytoplasmatic RNA contained hundreds and thousands of viral genomes. Viruses produced by the cultures involved are found to be identical or highly similar to nucleotid sequences of their nucleic acids.
作者通过病毒核酸与细胞核酸分子杂交的方法，研究了五种产生D型肿瘤病毒的细胞培养物。结果表明，所研究的细胞系的核DNA含有数十个乃至数百个病毒RNA基因组当量，而细胞质RNA则含有数百个乃至数千个病毒基因组。所涉及的培养物产生的病毒，其核酸的核苷酸序列被发现与其相同或高度相似。
