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[Integration and expression of the oncornavirus type D genome in transplantable cells].

作者信息

Zhdanov V M, Mazurenko N N, Bukrinskaia A G, Volkova M Ia, Kosiakova N P

出版信息

Vopr Onkol. 1975;21(8):64-8.

PMID:1166653
Abstract

The authors investigated five cell cultures producing oncornaviruses type D by the method of molecular hybridization of viral nucleic acids with cell nucleic acids. It was shown that nuclear DNA of the cell lines under study contained scores and hundreds of viral RNA genome-equivalents, while cytoplasmatic RNA contained hundreds and thousands of viral genomes. Viruses produced by the cultures involved are found to be identical or highly similar to nucleotid sequences of their nucleic acids.

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