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先切割,再电凝:一种影响括约肌切开术出血的电灼技术。

First cut, then blend: an electrocautery technique affecting bleeding at sphincterotomy.

作者信息

Gorelick A, Cannon M, Barnett J, Chey W, Scheiman J, Elta G

机构信息

Division of Gastroenterology, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, MI 48109-0362, USA.

出版信息

Endoscopy. 2001 Nov;33(11):976-80. doi: 10.1055/s-2001-17918.

Abstract

BACKGROUND AND STUDY AIMS

The use of pure cut electrocautery current for endoscopic sphincterotomy lowers pancreatitis rates following endoscopic retrograde cholangiopancreatography (ERCP), but at the expense of greater localized bleeding which partially obscures the endoscopic view. We hypothesized that localized bleeding could be decreased by using blended current at the end of the sphincterotomy, without losing the benefit associated with pure cut current of lower post-ERCP pancreatitis benefit.

PATIENTS AND METHODS

Patients undergoing sphincterotomy were randomly allocated to receive pure cut current alone or a sequential combination of pure cut then blended current. In the sequential combination patients, the first 75 - 80 % of the sphincterotomy was done using pure cut current at 30 W and the remainder completed at a blend 2 setting (pure cut plus coagulation current), also at 30 W.

RESULTS

142 patients were enrolled in the study. No statistical difference was noted between the two groups in the rates of overall pancreatitis or bleeding requiring transfusion. When comparing visible bleeding rates (more than a few drops), we found that there was significantly more bleeding (P < 0.05) in the pure cut group (31/75, 41 %) at the time of sphincterotomy compared with the sequential combination group (16/67, 23 %).

CONCLUSIONS

A sequential combination of pure cut and blended current for sphincterotomy caused less visible bleeding than pure cut alone. This occurred without a change in the rate of post-ERCP pancreatitis.

摘要

背景与研究目的

在内镜逆行胰胆管造影术(ERCP)后,使用纯切割电灼电流进行内镜括约肌切开术可降低胰腺炎发生率,但代价是局部出血增多,这部分遮挡了内镜视野。我们推测,在括约肌切开术结束时使用混合电流可减少局部出血,同时不丧失纯切割电流降低ERCP术后胰腺炎发生率的益处。

患者与方法

接受括约肌切开术的患者被随机分配,分别单独接受纯切割电流或先接受纯切割电流再接受混合电流的序贯组合。在序贯组合组中,括约肌切开术的前75 - 80%使用30W的纯切割电流完成,其余部分在混合2设置(纯切割加凝固电流)下以30W完成。

结果

142例患者纳入本研究。两组在总体胰腺炎发生率或需要输血的出血发生率方面无统计学差异。比较可见出血率(超过几滴)时,我们发现括约肌切开术时,纯切割组(31/75,41%)的出血明显多于序贯组合组(16/67,23%)(P < 0.05)。

结论

括约肌切开术采用纯切割与混合电流的序贯组合比单纯纯切割引起的可见出血更少。且ERCP术后胰腺炎发生率未发生变化。

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